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I4B3K5

- I4B3K5_TURPD

UniProt

I4B3K5 - I4B3K5_TURPD

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Turpa_1214

Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471SubstrateUniRule annotation
    Sitei257 – 2571Critical for catalysisUniRule annotation
    Metal bindingi352 – 3521Magnesium or manganeseUniRule annotation
    Sitei422 – 4221Critical for catalysis
    Binding sitei549 – 5491SubstrateUniRule annotation
    Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation
    Metal bindingi554 – 5541Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciTPAR869212:GLMM-1192-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported
    Gene namesi
    Ordered Locus Names:Turpa_1214Imported
    OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
    Taxonomic identifieri869212 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeTurneriella
    ProteomesiUP000006048: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3434 PotentialImportedAdd
    BLAST
    Chaini35 – 742708 PotentialImportedPRO_5000911343Add
    BLAST

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate bindingUniRule annotation

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    I4B3K5-1 [UniParc]FASTAAdd to Basket

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    MADSKSKIIW TKIDEAPALA TYSLLPIVNA FTKAAGVVVE TCDISLAGRI    50
    LANFPENLSE SQKVADGLAA LGKLVLLPEA NVIKLPNISA SIPQLKAAIK 100
    ELQSQGYKVP DYPEEPKTED EKAIKARYAK VLGSAVNPVL REGNSDRRVA 150
    RSVKEFAKKN PHKLGEWSKE CKSHVANMKA GDFFHNEKSV TIEDATDVKF 200
    EFEDKSGNKT VLKEKLSLKK GEVFDATFMS AKALRQFIED QLADAKAKNL 250
    LFSVHLKATM MKVSDPIIFG HFVSVYFKDV FAKHAATFQK LGVNPDLGLG 300
    DLYAKIKTLP DAERAEIEAD IQATYSVRPP LAMVDSAKGI TNLHAGNDVI 350
    IDASMPVVIR DSGKMWGPDG KLHECKAVIP DTSYAEFYQT GFDFCRQQGA 400
    FDPRVMGNVA NVGLMAQQAE EYGSHDKTFK APGDGVIRVI DAAGKVLTEH 450
    HVETGDIWRA CQTKDEAIRD WVKLAVRRAR ATGSPAVFWL TSARAHDAQI 500
    IAKVNTYLKE HDTSGLEIHI LSLVDAMQFT LERVKAGKDT ISVTGNVMRD 550
    YLTDLFPILE LNTSAKMLSI VPLLNGGGLF ETGAGGSAPK HVQQFQQEGY 600
    LRWDSTGEFL ALGVSLEHLA ATFKNAKAQV LADTIDKAFG KFLDNNKSPA 650
    RKVGEIDNRG SHFYFGLYWA QALAEQTADK ELQARFAPIA KQLTENEAKI 700
    DKELIDAQGK PVDMGGYFHP DDAKTAKAMR PSATLNSIID AI 742
    Length:742
    Mass (Da):81,285
    Last modified:September 5, 2012 - v1
    Checksum:i1220201EC922CCAB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002959 Genomic DNA. Translation: AFM11862.1.
    RefSeqiYP_006439368.1. NC_018020.1.

    Genome annotation databases

    EnsemblBacteriaiAFM11862; AFM11862; Turpa_1214.
    GeneIDi13128119.
    KEGGitpx:Turpa_1214.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002959 Genomic DNA. Translation: AFM11862.1 .
    RefSeqi YP_006439368.1. NC_018020.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFM11862 ; AFM11862 ; Turpa_1214 .
    GeneIDi 13128119.
    KEGGi tpx:Turpa_1214.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci TPAR869212:GLMM-1192-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1111 / DSM 21527 / NCTC 11395 / HImported.

    Entry informationi

    Entry nameiI4B3K5_TURPD
    AccessioniPrimary (citable) accession number: I4B3K5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3