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Protein

6-phosphofructokinase

Gene

Turpa_0990

Organism
Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.SAAS annotation

Catalytic activityi

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.SAAS annotation

Pathway:iglycolysis

This protein is involved in step 3 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.SAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (Turpa_3079)
  3. ATP-dependent 6-phosphofructokinase (pfkA), 6-phosphofructokinase (Turpa_0990)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAR869212:GLMM-967-MONOMER.
UniPathwayiUPA00109; UER00182.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphofructokinaseSAAS annotation (EC:2.7.1.11SAAS annotation)
Gene namesi
Ordered Locus Names:Turpa_0990Imported
OrganismiTurneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) (Leptospira parva)Imported
Taxonomic identifieri869212 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeTurneriella
ProteomesiUP000006048 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131 PotentialImportedAdd
BLAST
Chaini32 – 327296 PotentialImportedPRO_5000911241Add
BLAST

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

KOiK00850.

Family and domain databases

InterProiIPR022953. ATP_PFK.
IPR012003. ATP_PFK_prok-type.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 1 hit.
[Graphical view]
PIRSFiPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

I4B2Y2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTKVAKRIA ILTSGGDVPG LNACIRAVAL AAERSGFSIV GVAHGYDGLI
60 70 80 90 100
DGEFLHLETE VLRAAVPRGG TILRSARSKR FTTAEGRAEA AKQLRAAHID
110 120 130 140 150
SLVVIGGDGS LTGAAAFAAE HGFAVMGIPK TIDNDVEGTD VCIGFDTAVN
160 170 180 190 200
TAMQAIDRIR DTADSHARIF AVEVMGRDSG YLAWAAGMAG AADGILIPET
210 220 230 240 250
DADWRSLEEK LKERHKTRTG SLLVVVAEGD ETGGAAPVAK RLQAAFPEES
260 270 280 290 300
IGLCVLGHTQ RGGSPTASDR ILATRFAVAA VDAIAAGKSG MMTALVGDDI
310 320
RLVPIASVRR RPLALTPERL RLMEILI
Length:327
Mass (Da):34,186
Last modified:September 5, 2012 - v1
Checksum:iD2A72BEF87DDECBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002959 Genomic DNA. Translation: AFM11639.1.
RefSeqiWP_014802157.1. NC_018020.1.

Genome annotation databases

EnsemblBacteriaiAFM11639; AFM11639; Turpa_0990.
KEGGitpx:Turpa_0990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002959 Genomic DNA. Translation: AFM11639.1.
RefSeqiWP_014802157.1. NC_018020.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFM11639; AFM11639; Turpa_0990.
KEGGitpx:Turpa_0990.

Phylogenomic databases

KOiK00850.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00182.
BioCyciTPAR869212:GLMM-967-MONOMER.

Family and domain databases

InterProiIPR022953. ATP_PFK.
IPR012003. ATP_PFK_prok-type.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 1 hit.
[Graphical view]
PIRSFiPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1111 / DSM 21527 / NCTC 11395 / HImported.

Entry informationi

Entry nameiI4B2Y2_TURPD
AccessioniPrimary (citable) accession number: I4B2Y2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: July 22, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.