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Protein
Submitted name:

Macrophage migration inhibitory factor

Gene

MIF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Macrophage migration inhibitory factorImported
Gene namesi
Name:MIFImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000240972.1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiI4AY87

Expressioni

Gene expression databases

BgeeiENSG00000240972
ExpressionAtlasiI4AY87 baseline and differential

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
WDYHV1Q96HA83EBI-10287234,EBI-741158

GO - Molecular functioni

Protein-protein interaction databases

IntActiI4AY87, 1 interactor

Structurei

3D structure databases

SMRiI4AY87
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1759 Eukaryota
ENOG41122MF LUCA
KOiK07253
OMAiPDRIYIN
OrthoDBiEOG091G0ZNJ

Family and domain databases

Gene3Di3.30.429.10, 1 hit
InterProiView protein in InterPro
IPR001398 Macrophage_inhib_fac
IPR019829 Macrophage_inhib_fac_CS
IPR014347 Tautomerase/MIF_sf
PANTHERiPTHR11954 PTHR11954, 1 hit
PfamiView protein in Pfam
PF01187 MIF, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004816 Macrophage_inhib_fac, 1 hit
SUPFAMiSSF55331 SSF55331, 1 hit
PROSITEiView protein in PROSITE
PS01158 MIF, 1 hit

Sequencei

Sequence statusi: Fragment.

I4AY87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF
60 70 80 90 100
GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY
110
DMNAANVGWN NSTFA
Length:115
Mass (Da):12,476
Last modified:September 5, 2012 - v1
Checksum:i56D51107C05286B2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei115Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ846015 mRNA Translation: AFM09726.1
HF564790 Genomic DNA Translation: CCP37995.1
RefSeqiNP_002406.1, NM_002415.1
UniGeneiHs.407995

Genome annotation databases

GeneIDi4282
KEGGihsa:4282

Similar proteinsi

Entry informationi

Entry nameiI4AY87_HUMAN
AccessioniPrimary (citable) accession number: I4AY87
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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