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I4AH93

- I4AH93_FLELS

UniProt

I4AH93 - I4AH93_FLELS

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Protein

Alanine racemase

Gene

Fleli_0871

Organism
Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Sio-4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei36 – 361Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei135 – 1351SubstrateUniRule annotation
Active sitei278 – 2781Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei326 – 3261Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciFLIT880071:GLDC-870-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Fleli_0871Imported
OrganismiFlexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Sio-4)Imported
Taxonomic identifieri880071 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeFlexibacter
ProteomesiUP000006054: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei36 – 361N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI4AH93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I4AH93-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFSTSHIEIS KSALQNNYHF LRQLIGENVT LSSVVKGNAY GHGLENFIPL
60 70 80 90 100
AESCGASHFS VFSADEAFEV QKLKKENSQI MILGMIGNEE LEWAIRTSIE
110 120 130 140 150
VYMFDLERLE VGLQIAQKMQ MPIKIHLEME TGMNRIGIAK KDIPKVFQLL
160 170 180 190 200
TNYPNCYILE GISTHYAGAE SIANYVRVKQ QIINYKKIVK RFQRKENPAF
210 220 230 240 250
IPKKYHTACS AATIAYPQTR MDMVRIGILQ YGFFPTQETL IQYLKDNKTH
260 270 280 290 300
IDPLKRVLSW KSKIMTIKDV EAGEFIGYGT SFLASQKMKI AIVPVGYAHG
310 320 330 340 350
YSRSLSNMGR VLVRGERMAV VGVVNMNLMI IDLEKMQSAE IGDEVILIGK
360 370 380
QGEQEVSVAS FSEMSNQLNY ELLTRLPMNI PRKIVE
Length:386
Mass (Da):43,751
Last modified:September 5, 2012 - v1
Checksum:iB9C5A05C1D6A57B0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003345 Genomic DNA. Translation: AFM03328.1.
RefSeqiWP_014796786.1. NC_018018.1.
YP_006433121.1. NC_018018.1.

Genome annotation databases

EnsemblBacteriaiAFM03328; AFM03328; Fleli_0871.
GeneIDi13122688.
KEGGifli:Fleli_0871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003345 Genomic DNA. Translation: AFM03328.1 .
RefSeqi WP_014796786.1. NC_018018.1.
YP_006433121.1. NC_018018.1.

3D structure databases

ProteinModelPortali I4AH93.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFM03328 ; AFM03328 ; Fleli_0871 .
GeneIDi 13122688.
KEGGi fli:Fleli_0871.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci FLIT880071:GLDC-870-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Sio-4Imported.

Entry informationi

Entry nameiI4AH93_FLELS
AccessioniPrimary (citable) accession number: I4AH93
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: October 29, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3