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I3ZVF3 (I3ZVF3_9EURY) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Thymidine kinase HAMAP-Rule MF_00124

EC=2.7.1.21 HAMAP-Rule MF_00124
Gene names
Name:tdk HAMAP-Rule MF_00124
ORF Names:CL1_1488 EMBL AFL95687.1
OrganismThermococcus sp. CL1 [Complete proteome] EMBL AFL95687.1
Taxonomic identifier163003 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding13 – 208ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding91 – 944ATP By similarity HAMAP-Rule MF_00124

Sites

Active site921Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1481Zinc By similarity HAMAP-Rule MF_00124
Metal binding1511Zinc By similarity HAMAP-Rule MF_00124
Metal binding1861Zinc By similarity HAMAP-Rule MF_00124
Metal binding1891Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
I3ZVF3 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: CBAC4866319E161E

FASTA19321,353
        10         20         30         40         50         60 
MVHPGGFLEV ITGPMFAGKT TELIKRIERQ TFAKRKAALF KPAIDNRYSE DEVVAHNGLR 

        70         80         90        100        110        120 
YEAFVVSTDE DGVRRIVEIT RKGNYDVIGI DEVQFFPMDI VGALEELADE GVYVIASGLN 

       130        140        150        160        170        180 
LDFKAEPFPV TKELLVRADN IVYLTAVCTV CGKPATRSQR LIDGKPAPRD SPVILVGGSE 

       190 
SYEARCRGHH FVP 

« Hide

References

[1]"Complete Genome Sequence of the Hyperthermophilic Archaeon Thermococcus sp. Strain CL1, Isolated from a Paralvinella sp. Polychaete Worm Collected from a Hydrothermal Vent."
Jung J.H., Holden J.F., Seo D.H., Park K.H., Shin H., Ryu S., Lee J.H., Park C.S.
J. Bacteriol. 194:4769-4770(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]Jung J.-H., Lee J.-H., Holden J.F., Seo D.-H., Shin H., Ryu S., Park C.-S.
Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003651 Genomic DNA. Translation: AFL95687.1.
RefSeqYP_006425481.1. NC_018015.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFL95687; AFL95687; CL1_1488.
GeneID13037892.
KEGGthm:CL1_1488.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Enzyme and pathway databases

BioCycTSP163003:GLMB-1530-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI3ZVF3_9EURY
AccessionPrimary (citable) accession number: I3ZVF3
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: June 11, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)