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Protein

Elongation factor Tu

Gene

tuf

Organism
Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi82 – 865GTPUniRule annotation
Nucleotide bindingi137 – 1404GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTROS926566:GLM7-3736-MONOMER.
TROS926566:GLM7-908-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Terro_0908Imported, Terro_3738Imported
OrganismiTerriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63)Imported
Taxonomic identifieri926566 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeTerriglobus
ProteomesiUP000006056: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.
OMAiIKMTGEL.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I3ZL31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEKFDRSK PHVNVGTIGH IDHGKTTLTA AITKVLSKHN PKNSFRSFDT
60 70 80 90 100
IDNAPEERER GITIATSHVE YETANRHYAH VDCPGHADYI KNMITGAAQM
110 120 130 140 150
DGAILVVAAT DGPMPQTKEH VLLARQVGVP YIVVFLNKCD AVEDEELIDL
160 170 180 190 200
VEMEVRELLS KYDFPGDDVP VIRGSALGAL NGEAQWEAKI DELMDAVDKN
210 220 230 240 250
VPQPDRLVDL PFLMPIEDIF SISGRGTVVT GRIERGKIKV GEPAQIVGFR
260 270 280 290 300
DTQNTTVTGV EMFKKQLDEG LAGDNAGLLL RGTAKDDVER GMVLAKPGSI
310 320 330 340 350
TPHTTFKGEI YVLSKEEGGR HTPFFDGYRP QFYFRTTDVT GSAKLPAGTE
360 370 380 390
MVMPGDNIAL EITLHTPVAM EKGLRFAIRE GGRTVGAGTI SEIIK
Length:395
Mass (Da):43,163
Last modified:September 5, 2012 - v1
Checksum:iCEDBB9B6792589BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003379 Genomic DNA. Translation: AFL87234.1.
CP003379 Genomic DNA. Translation: AFL89949.1.
RefSeqiYP_006420569.1. NC_018014.1.
YP_006423284.1. NC_018014.1.

Genome annotation databases

EnsemblBacteriaiAFL87234; AFL87234; Terro_0908.
AFL89949; AFL89949; Terro_3738.
GeneIDi13039671.
13041798.
KEGGitrs:Terro_0908.
trs:Terro_3738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003379 Genomic DNA. Translation: AFL87234.1.
CP003379 Genomic DNA. Translation: AFL89949.1.
RefSeqiYP_006420569.1. NC_018014.1.
YP_006423284.1. NC_018014.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFL87234; AFL87234; Terro_0908.
AFL89949; AFL89949; Terro_3738.
GeneIDi13039671.
13041798.
KEGGitrs:Terro_0908.
trs:Terro_3738.

Phylogenomic databases

KOiK02358.
OMAiIKMTGEL.

Enzyme and pathway databases

BioCyciTROS926566:GLM7-3736-MONOMER.
TROS926566:GLM7-908-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 18391Imported and DSM 18391 / NRRL B-41598 / KBS 63Imported.

Entry informationi

Entry nameiI3ZL31_TERRK
AccessioniPrimary (citable) accession number: I3ZL31
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: March 4, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.