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I3ZC48 (I3ZC48_TERRK) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 7. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Terro_0475 EMBL AFL86816.1
OrganismTerriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) [Complete proteome] [HAMAP] EMBL AFL86816.1
Taxonomic identifier926566 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Acidobacteriales › Acidobacteriaceae › Terriglobus ›

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
I3ZC48 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: C96EC81D58EA55DA

FASTA46650,664
        10         20         30         40         50         60 
MQTSYNGIEV PVDGKAITYT NGAYSVPDNP IVPFIEGDGA GRDIWKNARK VLDAAVEKSY 

        70         80         90        100        110        120 
GGTKKVAWYE ILAGEKAYGL TQNWLPDDTV QACIDFRVSI KGPLTTPIGG GIRSLNVTLR 

       130        140        150        160        170        180 
QTMDLYQCIR PVKHYPGVPS PVINADDVDV VIFRENTEDI YAGIEFKAGS PEEAKLREFV 

       190        200        210        220        230        240 
NTQLLANTKK QLRSDGGIGI KPITEMASKR LVRAAIQYAV DHGRKVMSIV HKGNIQKFTE 

       250        260        270        280        290        300 
GAFREWGYEV AVTEFRDKIV TERESWILGA LDKDPNTPPE AIAKLVEPGL KFAPPSFEQK 

       310        320        330        340        350        360 
IIAEVKDVIA AIGATHGNGA WKKLILVNDR ICDAMFQDLL LKPQEYDVLA TTNLNGDYLS 

       370        380        390        400        410        420 
DAAAAQVGGL GIAPGSNIGD GYAVFEATHG TAPRLADQDV VNPGSVILSG AMLLQLIGWK 

       430        440        450        460 
EAADLVEKAM EKTISQKYVT VDFAKSMQGA TQVGTTAFSD RVIENM

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References

[1]"Complete genome of Terriglobus roseus DSM 18391."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Munk A.C.C., Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C. expand/collapse author list , Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Brambilla E., Klenk H.-P., Eisen J.A.
Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 18391 / NRRL B-41598 / KBS 63.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003379 Genomic DNA. Translation: AFL86816.1.
RefSeqYP_006420151.1. NC_018014.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFL86816; AFL86816; Terro_0475.
GeneID13039341.
KEGGtrs:Terro_0475.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Family and domain databases

Gene3D3.40.718.10. 2 hits.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI3ZC48_TERRK
AccessionPrimary (citable) accession number: I3ZC48
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: April 3, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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