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Protein

Thymidine kinase

Gene

tdk

Organism
Belliella baltica (strain DSM 15883 / CIP 108006 / LMG 21964 / BA134)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei97Proton acceptorUniRule annotation1
Metal bindingi153ZincUniRule annotation1
Metal bindingi156ZincUniRule annotation1
Metal bindingi185ZincUniRule annotation1
Metal bindingi188ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 31ATPUniRule annotation8
Nucleotide bindingi96 – 99ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciBBAL866536:G1H5P-586-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Belba_0572Imported
OrganismiBelliella baltica (strain DSM 15883 / CIP 108006 / LMG 21964 / BA134)Imported
Taxonomic identifieri866536 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCyclobacteriaceaeBelliella
Proteomesi
  • UP000006050 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857
OMAiKEQFGWI
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

I3Z1W1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFIEPFISIK NKKDKKGHIE VICGSMFSGK TEELIRRLNR ALIAKQKVEI
60 70 80 90 100
FKPSIDKRYH ELDVVSHNEN AIRSTPVNFA EDILLLAGDC DVVGIDEVQF
110 120 130 140 150
FDNHIVHIAN VLANGGKRVI LAGLDMDFEG KAFEPMPQLL AIAEYVTKVH
160 170 180 190
AICMKCGDLA SYSYRLSDTK DKVMLGEKDS YEARCRKCFY EEKN
Length:194
Mass (Da):22,019
Last modified:September 5, 2012 - v1
Checksum:i9E3BABC8C2E98A16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003281 Genomic DNA Translation: AFL83229.1
RefSeqiWP_014771242.1, NC_018010.1

Genome annotation databases

EnsemblBacteriaiAFL83229; AFL83229; Belba_0572
KEGGibbd:Belba_0572
PATRICifig|866536.3.peg.590

Similar proteinsi

Entry informationi

Entry nameiI3Z1W1_BELBD
AccessioniPrimary (citable) accession number: I3Z1W1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: March 28, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported