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I3Z1W1

- I3Z1W1_BELBD

UniProt

I3Z1W1 - I3Z1W1_BELBD

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Protein
Thymidine kinase
Gene
tdk, Belba_0572
Organism
Belliella baltica (strain DSM 15883 / CIP 108006 / LMG 21964 / BA134)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei97 – 971Proton acceptor By similarityUniRule annotation
Metal bindingi153 – 1531Zinc By similarityUniRule annotation
Metal bindingi156 – 1561Zinc By similarityUniRule annotation
Metal bindingi185 – 1851Zinc By similarityUniRule annotation
Metal bindingi188 – 1881Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi24 – 318ATP By similarityUniRule annotation
Nucleotide bindingi96 – 994ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciBBAL866536:GL8V-572-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Belba_0572Imported
OrganismiBelliella baltica (strain DSM 15883 / CIP 108006 / LMG 21964 / BA134)Imported
Taxonomic identifieri866536 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCyclobacteriaceaeBelliella
ProteomesiUP000006050: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I3Z1W1-1 [UniParc]FASTAAdd to Basket

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MFIEPFISIK NKKDKKGHIE VICGSMFSGK TEELIRRLNR ALIAKQKVEI    50
FKPSIDKRYH ELDVVSHNEN AIRSTPVNFA EDILLLAGDC DVVGIDEVQF 100
FDNHIVHIAN VLANGGKRVI LAGLDMDFEG KAFEPMPQLL AIAEYVTKVH 150
AICMKCGDLA SYSYRLSDTK DKVMLGEKDS YEARCRKCFY EEKN 194
Length:194
Mass (Da):22,019
Last modified:September 5, 2012 - v1
Checksum:i9E3BABC8C2E98A16
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003281 Genomic DNA. Translation: AFL83229.1.
RefSeqiWP_014771242.1. NC_018010.1.
YP_006405984.1. NC_018010.1.

Genome annotation databases

EnsemblBacteriaiAFL83229; AFL83229; Belba_0572.
GeneIDi13054998.
KEGGibbd:Belba_0572.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003281 Genomic DNA. Translation: AFL83229.1 .
RefSeqi WP_014771242.1. NC_018010.1.
YP_006405984.1. NC_018010.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFL83229 ; AFL83229 ; Belba_0572 .
GeneIDi 13054998.
KEGGi bbd:Belba_0572.

Phylogenomic databases

KOi K00857.

Enzyme and pathway databases

BioCyci BBAL866536:GL8V-572-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 15883 / CIP 108006 / LMG 21964 / BA134.

Entry informationi

Entry nameiI3Z1W1_BELBD
AccessioniPrimary (citable) accession number: I3Z1W1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: September 3, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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