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I3YU83

- I3YU83_AEQSU

UniProt

I3YU83 - I3YU83_AEQSU

Protein

Thymidine kinase

Gene

tdk

Organism
Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei94 – 941Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 288ATPUniRule annotation
    Nucleotide bindingi93 – 964ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciASUB746697:GL7Y-1052-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    Ordered Locus Names:Aeqsu_1052Imported
    OrganismiAequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3)Imported
    Taxonomic identifieri746697 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeAequorivita
    ProteomesiUP000006049: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I3YU83-1 [UniParc]FASTAAdd to Basket

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    MFLENTVNQK EQFGWIEVIS GSMFSGKSEE LIRRLKRAKF ARQKVEIFTP    50
    SIDTRYAEDA VTSHDSNQIR STPVPAAANI PILADNCDVV GIDEAQFFDD 100
    EIVKVCNDLA NRGVRVIVAG LDMDYKGNPF GPMPALMATA EYVTKVHAIC 150
    TRTGNLAHYS YRKAKSEALV LLGETEEYEP LSRAAFFKAH LRDKVVKLEV 200
    KEAEEINNEK AAEKTGKQA 219
    Length:219
    Mass (Da):24,430
    Last modified:September 5, 2012 - v1
    Checksum:i178DA99D30B34F67
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003280 Genomic DNA. Translation: AFL80551.1.
    RefSeqiYP_006417566.1. NC_018013.1.

    Genome annotation databases

    EnsemblBacteriaiAFL80551; AFL80551; Aeqsu_1052.
    GeneIDi13044437.
    KEGGiasl:Aeqsu_1052.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003280 Genomic DNA. Translation: AFL80551.1 .
    RefSeqi YP_006417566.1. NC_018013.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFL80551 ; AFL80551 ; Aeqsu_1052 .
    GeneIDi 13044437.
    KEGGi asl:Aeqsu_1052.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci ASUB746697:GL7Y-1052-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14238 / LMG 21431 / ACAM 643 / 9-3Imported.

    Entry informationi

    Entry nameiI3YU83_AEQSU
    AccessioniPrimary (citable) accession number: I3YU83
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3