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Protein

Glutamate decarboxylase

Gene

Alfi_2924

Organism
Alistipes finegoldii (strain DSM 17242 / JCM 16770 / AHN 2437 / CCUG 46020 / CIP 107999)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciAFIN679935:GL7P-2923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Alfi_2924Imported
OrganismiAlistipes finegoldii (strain DSM 17242 / JCM 16770 / AHN 2437 / CCUG 46020 / CIP 107999)Imported
Taxonomic identifieri679935 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesRikenellaceaeAlistipes
ProteomesiUP000006052 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

I3YQA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQQRHTNED TLTDIFGSEE MRNPAPTEFI PKGKTSPEIA YQLVKDETYP
60 70 80 90 100
QTQPRLNLAT FVTTYMDDYA TRLMNEAINV NYIDETEYPR VAVMCGRCLN
110 120 130 140 150
IVANLWNTPE KAEWKTGALG IGSSEACMLG GVAAWLRWRN RRKAAGKPFD
160 170 180 190 200
KPNLVMSAGF QVVWEKFCQL WQIELRTVPL TLDHITLDPK QALEMCDENT
210 220 230 240 250
ICIVPIAGVT WTGLDDDIEG LDKALDEYNA KTGYEIPIHV DAASGGFILP
260 270 280 290 300
FLKPEKKWDF RLKWVLSIST SGHKYGLVYP GLGWVVWKDK KYLPDEMSFS
310 320 330 340 350
VNYLGANITQ VGLNFSRPAA QILGQYYNFI RLGFEGYKEI QQNSMDVAKY
360 370 380 390 400
CHQQIGTMKC FKNYSKEVVN PLFIWMMDPE YDKKAKWTLF DLQAKLQQSG
410 420 430 440 450
WMVPAYTMPK NIENVVVMRI VVRQGMSRDM ADMLMGDIRN AVAEFEQLEY
460 470
PTTSRIKYDN MEHQKGKVFT H
Length:471
Mass (Da):54,064
Last modified:September 4, 2012 - v1
Checksum:i50F0A6D9DB7024D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003274 Genomic DNA. Translation: AFL79172.1.
RefSeqiYP_006411857.1. NC_018011.1.

Genome annotation databases

EnsemblBacteriaiAFL79172; AFL79172; Alfi_2924.
KEGGiafd:Alfi_2924.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003274 Genomic DNA. Translation: AFL79172.1.
RefSeqiYP_006411857.1. NC_018011.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFL79172; AFL79172; Alfi_2924.
KEGGiafd:Alfi_2924.

Phylogenomic databases

KOiK01580.

Enzyme and pathway databases

BioCyciAFIN679935:GL7P-2923-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 17242 / JCM 16770 / AHN 2437 / CCUG 46020 / CIP 107999Imported.

Entry informationi

Entry nameiI3YQA4_ALIFI
AccessioniPrimary (citable) accession number: I3YQA4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 4, 2012
Last sequence update: September 4, 2012
Last modified: March 31, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.