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Protein

Elongation factor Tu

Gene

tuf

Organism
Alistipes finegoldii (strain DSM 17242 / JCM 16770 / AHN 2437 / CCUG 46020 / CIP 107999)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAFIN679935:GL7P-2042-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Alfi_2042Imported
OrganismiAlistipes finegoldii (strain DSM 17242 / JCM 16770 / AHN 2437 / CCUG 46020 / CIP 107999)Imported
Taxonomic identifieri679935 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesRikenellaceaeAlistipes
ProteomesiUP000006052 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I3YMX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEKFDRSK PHVNIGTIGH VDHGKTTLTA AITTVLAKKG LSELRSFDSI
60 70 80 90 100
DNAPEEKERG ITINTSHVEY QTANRHYAHV DCPGHADYVK NMVTGAAQMD
110 120 130 140 150
GAILVVAATD GPMPQTNEHV LLARQVNVPR IVVFLNKCDM VDDPEMLDLV
160 170 180 190 200
EMEVRDLLSK YEYDGDNAPV IRGSALGGLN GEPAWEDKIM ELMNAVDEYI
210 220 230 240 250
PIPQRENEKP FLMPVEDVFS ITGRGTVVTG RIETGIIHVG DPVEIVGLEE
260 270 280 290 300
KTLTSTCTGV EMFRKLLDEG EAGDNVGLLL RGIDKKEVKR GMVVAKPGSI
310 320 330 340 350
TPHTEFEAEV YILKKEEGGR HTPFHNNYRP QFYLRTMDVT GEVHLPAGVD
360 370 380 390
MVMPGDHVTI TVKLIYPVAI NEGLRFAIRE GGRTVGAGQI LKIVK
Length:395
Mass (Da):43,484
Last modified:September 5, 2012 - v1
Checksum:i6A92ED8249B16632
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003274 Genomic DNA. Translation: AFL78346.1.
RefSeqiWP_009596396.1. NC_018011.1.
YP_006411031.1. NC_018011.1.

Genome annotation databases

EnsemblBacteriaiAFL78346; AFL78346; Alfi_2042.
KEGGiafd:Alfi_2042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003274 Genomic DNA. Translation: AFL78346.1.
RefSeqiWP_009596396.1. NC_018011.1.
YP_006411031.1. NC_018011.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFL78346; AFL78346; Alfi_2042.
KEGGiafd:Alfi_2042.

Phylogenomic databases

KOiK02358.

Enzyme and pathway databases

BioCyciAFIN679935:GL7P-2042-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DSM 17242 / JCM 16770 / AHN 2437 / CCUG 46020 / CIP 107999Imported.

Entry informationi

Entry nameiI3YMX8_ALIFI
AccessioniPrimary (citable) accession number: I3YMX8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: June 24, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.