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I3XX34 (I3XX34_SULBS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Sulba_1214 EMBL AFL68508.1
OrganismSulfurospirillum barnesii (strain ATCC 700032 / DSM 10660 / SES-3) [Complete proteome] [HAMAP] EMBL AFL68508.1
Taxonomic identifier760154 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeSulfurospirillum

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain133 – 327195ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding160 – 21152ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2831Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2951Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2951Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2971Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
I3XX34 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: 80BE4FCCDBB7AA8C

FASTA34439,275
        10         20         30         40         50         60 
MKIAVLFGAQ SFEHEISVVS AIALKKVLKS EIVYIFCDYE RNFYLIPTDT INAKRFSSGA 

        70         80         90        100        110        120 
YKKDKSLVLK QGGFFAQKMF GEEKVAFDVL INLVHGRDGE DGKLSSLLEF FAIPYIGPRI 

       130        140        150        160        170        180 
EGSCISYNKL FTKLYAKEVG VDVLDYQVLH KESKDDIRIA YPFIVKPLRL GSSIGIGIVK 

       190        200        210        220        230        240 
DEKELSYALD VAFEFDDTVL IEPFMQGVKE YNLAGCKTDG FIFSIIEEPQ KEEFLDFDKK 

       250        260        270        280        290        300 
YLDFSRTKRV TEAHLDVKIQ EKIREAFVKL YDPLFLGALI RCDFFVIDET IYLNEINPIP 

       310        320        330        340 
GSMANYLFDD FDTIITSLAQ YLPRTTTVMK AYHYIHSIQA AKGK 

« Hide

References

[1]"Complete sequence of Sulfurospirillum barnesii SES-3."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Stolz J. expand/collapse author list , Arkin A., Dehal P., Oremland R., Saltikov C., Basu P., Hollibaugh J., Newman D., Stolyar S., Hazen T., Woyke T.
Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700032 / DSM 10660 / SES-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003333 Genomic DNA. Translation: AFL68508.1.
RefSeqYP_006404083.1. NC_018002.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFL68508; AFL68508; Sulba_1214.
GeneID13059654.
KEGGsba:Sulba_1214.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycSBAR760154:GLLZ-1214-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI3XX34_SULBS
AccessionPrimary (citable) accession number: I3XX34
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 19, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)