ID   I3XEK9_SINF2            Unreviewed;       510 AA.
AC   I3XEK9;
DT   05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2012, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE            EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN   Name=gabD7 {ECO:0000313|EMBL:AFL54315.1};
GN   ORFNames=USDA257_c58040 {ECO:0000313|EMBL:AFL54315.1};
OS   Sinorhizobium fredii (strain USDA 257).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=1185652 {ECO:0000313|EMBL:AFL54315.1, ECO:0000313|Proteomes:UP000006180};
RN   [1] {ECO:0000313|EMBL:AFL54315.1, ECO:0000313|Proteomes:UP000006180}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA 257 {ECO:0000313|EMBL:AFL54315.1,
RC   ECO:0000313|Proteomes:UP000006180};
RX   PubMed=22843606; DOI=10.1128/JB.00966-12;
RA   Schuldes J., Rodriguez Orbegoso M., Schmeisser C., Krishnan H.B.,
RA   Daniel R., Streit W.R.;
RT   "Complete genome sequence of the broad-host-range strain Sinorhizobium
RT   fredii USDA257.";
RL   J. Bacteriol. 194:4483-4483(2012).
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP003563; AFL54315.1; -; Genomic_DNA.
DR   RefSeq; WP_014766420.1; NC_018000.1.
DR   AlphaFoldDB; I3XEK9; -.
DR   STRING; 1185652.USDA257_c58040; -.
DR   KEGG; sfd:USDA257_c58040; -.
DR   PATRIC; fig|1185652.3.peg.6026; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_1_2_5; -.
DR   Proteomes; UP000006180; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07130; ALDH_F7_AASADH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR044638; ALDH7A1-like.
DR   PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          32..488
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        264
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   510 AA;  54067 MW;  C4FC06DEEB9B50E8 CRC64;
     MNIAATKVDV AKEAAALLDK MGVARELYTG GDMPSYSPVT GEQIASLKTV SAAEAAGKIE
     QADEAFRAWR LVPAPKRGEL VRLLGEELRA FKADLGRLVS LEAGKIPSEG LGEVQEMIDI
     CDFAVGLSRQ LYGLTIATER PGHRMMETWH PLGVVGIISA FNFPVAVWSW NAALALVCGN
     AVVWKPSEKT PLTALACEAI LERALARFGD APAGLSQVLI GDRAIGEVLV DHPKVPLVSA
     TGSTRMGRDV GPRLAKRFAR AILELGGNNA GIVCPSADLD MALRAIAFGA MGTAGQRCTT
     LRRLFVHESV YDQLVPRLKK AYQSVSVGNP LESTALVGPL VDKAAFDSMQ KAIAEAKSEG
     GAVTGGERVE LGYENGYYVK PALVEMPKQV GPVLEETFAP ILYVMKYSDF DAVVADHNAV
     AAGLSSSIFT RDMQESERFL AADGSDCGIA NVNIGTSGAE IGGAFGGEKE TGGGRESGSD
     AWRAYMRRAT NTINYSKALP LAQGVSFDIE
//