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I3WYZ4

- I3WYZ4_RHIFR

UniProt

I3WYZ4 - I3WYZ4_RHIFR

Protein

Alanine racemase

Gene

USDA257_c02520

Organism
Sinorhizobium fredii USDA 257
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei51 – 511Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei150 – 1501SubstrateUniRule annotation
    Active sitei272 – 2721Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei320 – 3201Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    ORF Names:USDA257_c02520Imported
    OrganismiSinorhizobium fredii USDA 257Imported
    Taxonomic identifieri1185652 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
    ProteomesiUP000006180: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei51 – 511N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliI3WYZ4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I3WYZ4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDRHALHIQG REAEAGAGAS GYLTIDLAAL RRNYQKLSAA VAPATVAAVV    50
    KADAYGLGAQ QVSKALHAQG CRQFFVAHLA EAIELRSLLP NDTQIAVLNG 100
    LQPGAEITCA KANIVPVLNS LEQFRRWSFT AQKLGRVLPT VLQFDTGMSR 150
    LGVPLQERTA LAAVLKDCRS IEILFIMSHL ACADEVDNKQ NADQLAEMRL 200
    IAAEFADLDV CFANSGGVFL GRDYHGALSR PGIALYGGAP IAGRPNPIEP 250
    VVRLDVAVIQ TRTVPAGTRV GYGGAHVTSA ETRLATIAAG YADGLPRSLS 300
    DRGAVFFDGV RLPIVGRVSM DSITVDITAL PEGTLSLGSL VEVLGPHQTL 350
    EDVAEAAGTI SYEILTGLGR RYERRYR 377
    Length:377
    Mass (Da):40,135
    Last modified:September 5, 2012 - v1
    Checksum:iE152582DDBC2CF8C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003563 Genomic DNA. Translation: AFL48850.1.
    RefSeqiWP_014761047.1. NC_018000.1.
    YP_006395607.1. NC_018000.1.

    Genome annotation databases

    EnsemblBacteriaiAFL48850; AFL48850; USDA257_c02520.
    GeneIDi13062665.
    KEGGisfd:USDA257_c02520.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003563 Genomic DNA. Translation: AFL48850.1 .
    RefSeqi WP_014761047.1. NC_018000.1.
    YP_006395607.1. NC_018000.1.

    3D structure databases

    ProteinModelPortali I3WYZ4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFL48850 ; AFL48850 ; USDA257_c02520 .
    GeneIDi 13062665.
    KEGGi sfd:USDA257_c02520.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of the Broad-Host-Range Strain Sinorhizobium fredii USDA257."
      Schuldes J., Rodriguez Orbegoso M., Schmeisser C., Krishnan H.B., Daniel R., Streit W.R.
      J. Bacteriol. 194:4483-4483(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: USDA 257Imported.

    Entry informationi

    Entry nameiI3WYZ4_RHIFR
    AccessioniPrimary (citable) accession number: I3WYZ4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3