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I3WYZ4

- I3WYZ4_RHIFR

UniProt

I3WYZ4 - I3WYZ4_RHIFR

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Protein

Alanine racemase

Gene

USDA257_c02520

Organism
Sinorhizobium fredii USDA 257
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei150 – 1501SubstrateUniRule annotation
Active sitei272 – 2721Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei320 – 3201Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:USDA257_c02520Imported
OrganismiSinorhizobium fredii USDA 257Imported
Taxonomic identifieri1185652 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000006180: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei51 – 511N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI3WYZ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I3WYZ4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDRHALHIQG REAEAGAGAS GYLTIDLAAL RRNYQKLSAA VAPATVAAVV
60 70 80 90 100
KADAYGLGAQ QVSKALHAQG CRQFFVAHLA EAIELRSLLP NDTQIAVLNG
110 120 130 140 150
LQPGAEITCA KANIVPVLNS LEQFRRWSFT AQKLGRVLPT VLQFDTGMSR
160 170 180 190 200
LGVPLQERTA LAAVLKDCRS IEILFIMSHL ACADEVDNKQ NADQLAEMRL
210 220 230 240 250
IAAEFADLDV CFANSGGVFL GRDYHGALSR PGIALYGGAP IAGRPNPIEP
260 270 280 290 300
VVRLDVAVIQ TRTVPAGTRV GYGGAHVTSA ETRLATIAAG YADGLPRSLS
310 320 330 340 350
DRGAVFFDGV RLPIVGRVSM DSITVDITAL PEGTLSLGSL VEVLGPHQTL
360 370
EDVAEAAGTI SYEILTGLGR RYERRYR
Length:377
Mass (Da):40,135
Last modified:September 5, 2012 - v1
Checksum:iE152582DDBC2CF8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003563 Genomic DNA. Translation: AFL48850.1.
RefSeqiWP_014761047.1. NC_018000.1.
YP_006395607.1. NC_018000.1.

Genome annotation databases

EnsemblBacteriaiAFL48850; AFL48850; USDA257_c02520.
GeneIDi13062665.
KEGGisfd:USDA257_c02520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003563 Genomic DNA. Translation: AFL48850.1 .
RefSeqi WP_014761047.1. NC_018000.1.
YP_006395607.1. NC_018000.1.

3D structure databases

ProteinModelPortali I3WYZ4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFL48850 ; AFL48850 ; USDA257_c02520 .
GeneIDi 13062665.
KEGGi sfd:USDA257_c02520.

Phylogenomic databases

KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of the Broad-Host-Range Strain Sinorhizobium fredii USDA257."
    Schuldes J., Rodriguez Orbegoso M., Schmeisser C., Krishnan H.B., Daniel R., Streit W.R.
    J. Bacteriol. 194:4483-4483(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: USDA 257Imported.

Entry informationi

Entry nameiI3WYZ4_RHIFR
AccessioniPrimary (citable) accession number: I3WYZ4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: November 26, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3