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I3WYZ4 (I3WYZ4_RHIFR) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site511Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2721Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1501Substrate By similarity HAMAP-Rule MF_01201
Binding site3201Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue511N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I3WYZ4 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: E152582DDBC2CF8C

FASTA37740,135
        10         20         30         40         50         60 
MDRHALHIQG REAEAGAGAS GYLTIDLAAL RRNYQKLSAA VAPATVAAVV KADAYGLGAQ 

        70         80         90        100        110        120 
QVSKALHAQG CRQFFVAHLA EAIELRSLLP NDTQIAVLNG LQPGAEITCA KANIVPVLNS 

       130        140        150        160        170        180 
LEQFRRWSFT AQKLGRVLPT VLQFDTGMSR LGVPLQERTA LAAVLKDCRS IEILFIMSHL 

       190        200        210        220        230        240 
ACADEVDNKQ NADQLAEMRL IAAEFADLDV CFANSGGVFL GRDYHGALSR PGIALYGGAP 

       250        260        270        280        290        300 
IAGRPNPIEP VVRLDVAVIQ TRTVPAGTRV GYGGAHVTSA ETRLATIAAG YADGLPRSLS 

       310        320        330        340        350        360 
DRGAVFFDGV RLPIVGRVSM DSITVDITAL PEGTLSLGSL VEVLGPHQTL EDVAEAAGTI 

       370 
SYEILTGLGR RYERRYR 

« Hide

References

[1]"Complete Genome Sequence of the Broad-Host-Range Strain Sinorhizobium fredii USDA257."
Schuldes J., Rodriguez Orbegoso M., Schmeisser C., Krishnan H.B., Daniel R., Streit W.R.
J. Bacteriol. 194:4483-4483(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: USDA 257 EMBL AFL48850.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003563 Genomic DNA. Translation: AFL48850.1.
RefSeqYP_006395607.1. NC_018000.1.

3D structure databases

ProteinModelPortalI3WYZ4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFL48850; AFL48850; USDA257_c02520.
GeneID13062665.
KEGGsfd:USDA257_c02520.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI3WYZ4_RHIFR
AccessionPrimary (citable) accession number: I3WYZ4
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 19, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)