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I3WWD7

- I3WWD7_ONCMY

UniProt

I3WWD7 - I3WWD7_ONCMY

Protein
Submitted name:

Plasminogen activator inhibitor 1

Gene

serpine1

Organism
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei64 – 641Sulfate; via amide nitrogenImported
    Binding sitei317 – 3171SulfateImported

    Protein family/group databases

    MEROPSiI04.020.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Plasminogen activator inhibitor 1Imported
    Gene namesi
    Name:serpine1Imported
    OrganismiOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)Imported
    Taxonomic identifieri8022 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeOncorhynchus

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: InterPro

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4KDSX-ray1.67A15-391[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the serpin family.UniRule annotation

    Family and domain databases

    InterProiIPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view]
    PANTHERiPTHR11461. PTHR11461. 1 hit.
    PfamiPF00079. Serpin. 1 hit.
    [Graphical view]
    SMARTiSM00093. SERPIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF56574. SSF56574. 1 hit.
    PROSITEiPS00284. SERPIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I3WWD7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLCLYVGFFL GLSGAAISNL QEKQTDFGMR VFSQVAQNSK GSNLAFSPYG    50
    VATILAMAQL GAGGNTLKTL NAKLGFSLQE RGMARQQRLL QRDISSEEGV 100
    ELASGVMVER KMALEKGFRR GLGKAFQASP HQLDFSRPDQ ALDIINAWVS 150
    DHTAGTIPSF LSSGALTDET RMVLLNALHF QGLWKVPFDP KMTEERLFHC 200
    ANGSSVPVPM MRLTHRFKYG EFVTPDGVDY DVIEVPYEGE SLSMLLVSPF 250
    EPETPVSSLS SELTTQRLQQ WRQEMRSVKR QLVLPRFTLD SEVELKSILI 300
    QMGLGDMFNL AKADFTRITT EQPLCVSKVL QKVKIEVNEE GTKASAATAA 350
    ILFSRMAVEE ITMNRPFLFL IHHKSTGAVL FMGQVNQPQQ H 391
    Length:391
    Mass (Da):43,428
    Last modified:September 5, 2012 - v1
    Checksum:i5A6FFC801ECEEFE7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JQ801453 mRNA. Translation: AFL47815.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JQ801453 mRNA. Translation: AFL47815.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4KDS X-ray 1.67 A 15-391 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I04.020.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view ]
    PANTHERi PTHR11461. PTHR11461. 1 hit.
    Pfami PF00079. Serpin. 1 hit.
    [Graphical view ]
    SMARTi SM00093. SERPIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56574. SSF56574. 1 hit.
    PROSITEi PS00284. SERPIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of Fish PAI-1."
      Bager R., Johansen J.S., Jensen J.K., Stensballe A., Jendroszek A., Sorensen H.P., Andreasen P.A.
      Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Protein conformational change delayed by steric hindrance from an N-linked glycan."
      Bager R., Johansen J.S., Jensen J.K., Stensballe A., Jendroszek A., Buxbom L., Sorensen H.P., Andreasen P.A.
      J. Mol. Biol. 425:2867-2877(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.67 ANGSTROMS) OF 15-391.

    Entry informationi

    Entry nameiI3WWD7_ONCMY
    AccessioniPrimary (citable) accession number: I3WWD7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3