I3TLS5 (I3TLS5_TISMK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:

TMO_1874 EMBL AFK53713.1

Organism

Tistrella mobilis (strain KA081020-065) [Complete proteome] [HAMAP] EMBL AFK53713.1

Taxonomic identifier

1110502 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Tistrella › Tistrella mobilis

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I3TLS5 [UniParc]. Last modified September 5, 2012. Version 1. Checksum: DDE662A4BEFA99E0	FASTA	408	42,856
	10 20 30 40 50 60 MSTPLTALPA APAAPPPAWI EIDLDALAEN HARLTGLMRA HNPAAEVTGV IKADGYGLGA 70 80 90 100 110 120 DIVGPALARA GAPALFVAHL SEGAALRRAL RADPDPARHA LPVYILNGMA EGERADFLAF 130 140 150 160 170 180 DLRPVLNGPD DLDRWTRAGQ AQGGPLPAAL HIDTGMSRLG FDEAGFKALA ADPARLGGVD 190 200 210 220 230 240 IRITMSHLAC ADDPAHPLNR RQLDRFRAVT AVVGRGRLSL ANSSGLFLGP DFHFDLGRPG 250 260 270 280 290 300 VALYGVNPVP GHPNPMVPVV RLKARVLQVR TIDSFESVGY GAAARARPGM RVATLAIGYA 310 320 330 340 350 360 DGWPWSAAGK GEVVIAGHRA PILGRVSMDL VTVDVSTLPE PLIHGGAVAE LIGDHRDIDA 370 380 390 400 LAKDAGTIGY EILTRLGRRY ARQPMTSGQT QVYPIGVPTP QTEVDPAP

References

[1]

"Bacterial biosynthesis and maturation of the didemnin anti-cancer agents." Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H., Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y. J. Am. Chem. Soc. 134:8625-8632(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KA081020-065 EMBL AFK53713.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003236 Genomic DNA. Translation: AFK53713.1.
RefSeq	YP_006371297.1. NC_017956.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFK53713; AFK53713; TMO_1874.
GeneID	13004988.
KEGG	tmo:TMO_1874.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I3TLS5_TISMK

Accession

Primary (citable) accession number: I3TLS5

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2012
Last sequence update:	September 5, 2012
Last modified:	April 3, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)