Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

I3THL5 (I3THL5_TISMK) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:TMO_0414 EMBL AFK52253.1
OrganismTistrella mobilis (strain KA081020-065) [Complete proteome] [HAMAP] EMBL AFK52253.1
Taxonomic identifier1110502 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeTistrella

Protein attributes

Sequence length931 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. SAAS SAAS022805 HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS021135

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1591 By similarity HAMAP-Rule MF_00595
Active site5931 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
I3THL5 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: C72EE89AA31BA647

FASTA931102,103
        10         20         30         40         50         60 
MSDDDGMTRG PARAANGNGS DAALKDDIRF LGRILGDIVR LNEGAEVFDL VERIRQTSIR 

        70         80         90        100        110        120 
FHRDEDRAAH DELDALLGGM DTVQGLKIVR AFSYFSHLAN IAEDQDRLRQ SRAGMPDGDG 

       130        140        150        160        170        180 
PAAGTLDYAM ARAATDGLDP DRLAAFFDTA RVGPVLTAHP TEVRRKSTLT REAEIARLLD 

       190        200        210        220        230        240 
RRDRERPQGE EAAAIEEEVT RAVLTLWQTA MLRRTRLTVI DEVVNGLSYY DETFLTEVPA 

       250        260        270        280        290        300 
VHARVEDMLA RRAGSTAEAR AGVASFLKMG SWIGGDRDGN PFVTADVLRT TMRLHTRQAM 

       310        320        330        340        350        360 
KFYLAELHEL GAELSLSATL VPVSDDLAAL AAASPVTPEH QRQEPYRLAV AGIHARMAAT 

       370        380        390        400        410        420 
AEALDAADAV TRPVPAAPRY ADPAGLARDL DVVHESLVAN GSVLLARGRL RRLRRAVDCF 

       430        440        450        460        470        480 
GFHLAVLDLR QNSAVHERTV AELLEVAAPG TDYLSLDEEA RIAVLERELA TTRPLVSPFA 

       490        500        510        520        530        540 
KYCEETTAEF AIFAEAAATH RRLGPQAIEN VIISKTDGAS DLLELALLLK EVGLVRPDGT 

       550        560        570        580        590        600 
AAVNIVPLFE TIADLRAAPQ IMRRVFACPA YRRLVASRGE MQEVMLGYSD SNKDGGFVTS 

       610        620        630        640        650        660 
RWELYKAETE LVACFREAGV ALRLFHGRGG SVGRGGGSAY DAILAQPAGA VGGRIRVTEQ 

       670        680        690        700        710        720 
GEIISSKYAN PGLGRRNLET FVAATLEASL LPQPACADLE ADMAAMEELS DTAFTAYRAL 

       730        740        750        760        770        780 
VYETPGFEDY FWASTVITEI ASLNIGSRPA SRSRTRRIED LRAIPWVFSW SQCRAMLPGW 

       790        800        810        820        830        840 
YGFGAAVTAW RDRHGEAGLD RLRRMYRDWP FFTTLLSNME MVLAKTSMAI ASRYAELVPD 

       850        860        870        880        890        900 
EALREAVFGR IRAEWQSSEA ALLAITGQTM VLERTPQLAR SIRDRFPYLD PLNHVQVEML 

       910        920        930 
RQHRSEAGSD RHLSGIHLTI NGISAGLRNS G 

« Hide

References

[1]"Bacterial biosynthesis and maturation of the didemnin anti-cancer agents."
Xu Y., Kersten R.D., Nam S.J., Lu L., Al-Suwailem A.M., Zheng H., Fenical W., Dorrestein P.C., Moore B.S., Qian P.Y.
J. Am. Chem. Soc. 134:8625-8632(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KA081020-065 EMBL AFK52253.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003236 Genomic DNA. Translation: AFK52253.1.
RefSeqYP_006369837.1. NC_017956.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFK52253; AFK52253; TMO_0414.
GeneID13003517.
KEGGtmo:TMO_0414.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.
OMAAIPWVFG.

Enzyme and pathway databases

BioCycTMOB1110502:GLMJ-422-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI3THL5_TISMK
AccessionPrimary (citable) accession number: I3THL5
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 19, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)