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I3RBS0

- I3RBS0_9EURY

UniProt

I3RBS0 - I3RBS0_9EURY

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Pyrococcus sp. ST04
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (05 Sep 2012)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciPSP1183377:GLJ2-77-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    ORF Names:Py04_0074Imported
    OrganismiPyrococcus sp. ST04Imported
    Taxonomic identifieri1183377 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
    ProteomesiUP000006467: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I3RBS0-1 [UniParc]FASTAAdd to Basket

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    MSTQHPDNYS IPFFSHSPVL GGEDEITEAF YAYSVLGADE QMWDFEGKEV    50
    DEFVVKKLLE RYPMFFKKKI LGKDLRLTPR VPNPSVEKAE AKLLLETLQG 100
    ITRAADYARI FYNDSIAPIF EVILPMTTSS AELERVYQLY KKIVGISSEV 150
    IHDVTVGEWI GEFYPEEIRI IPLFETKSAL LKSSRIVKEF LKDKDFEHQR 200
    VFFARSDPAM NYGLITAVTY VKKALYELAK LEEEMSISLY PIVGVGGPPF 250
    RGGMRPDNVD VVLEEYPSVQ TYTIQSSFKF DYPARDVVKA VDKIKSTKRR 300
    APTPVDIPEF LTAYEVEYQN QIKLLAPHIR RLASRIPDRR RRKLHIGLFG 350
    YARNVNGLAL PRAIKFTASL YSIGLPPELL ALNSVTDKDL ERVSEYYLHV 400
    YDDLEFAMKF FSFKVAEEVG LKKLAERVRE FKPDQIQEYV EEAELVFRGE 450
    GDVMKLAQMR GFLG 464
    Length:464
    Mass (Da):53,287
    Last modified:September 5, 2012 - v1
    Checksum:i7DD6E0511441E7F8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003534 Genomic DNA. Translation: AFK21680.1.
    RefSeqiWP_014733206.1. NC_017946.1.
    YP_006353755.1. NC_017946.1.

    Genome annotation databases

    EnsemblBacteriaiAFK21680; AFK21680; Py04_0074.
    GeneIDi13021297.
    KEGGipys:Py04_0074.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003534 Genomic DNA. Translation: AFK21680.1 .
    RefSeqi WP_014733206.1. NC_017946.1.
    YP_006353755.1. NC_017946.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFK21680 ; AFK21680 ; Py04_0074 .
    GeneIDi 13021297.
    KEGGi pys:Py04_0074.

    Phylogenomic databases

    KOi K01595.

    Enzyme and pathway databases

    BioCyci PSP1183377:GLJ2-77-MONOMER.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of the Hyperthermophilic Archaeon Pyrococcus sp. Strain ST04, Isolated from a Deep-Sea Hydrothermal Sulfide Chimney on the Juan de Fuca Ridge."
      Jung J.H., Lee J.H., Holden J.F., Seo D.H., Shin H., Kim H.Y., Kim W., Ryu S., Park C.S.
      J. Bacteriol. 194:4434-4435(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ST04Imported.

    Entry informationi

    Entry nameiI3RBS0_9EURY
    AccessioniPrimary (citable) accession number: I3RBS0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2012
    Last sequence update: September 5, 2012
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3