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I3RBS0

- I3RBS0_9EURY

UniProt

I3RBS0 - I3RBS0_9EURY

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppcA, Py04_0074
Organism
Pyrococcus sp. ST04
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciPSP1183377:GLJ2-77-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
ORF Names:Py04_0074Imported
OrganismiPyrococcus sp. ST04Imported
Taxonomic identifieri1183377 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000006467: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

I3RBS0-1 [UniParc]FASTAAdd to Basket

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MSTQHPDNYS IPFFSHSPVL GGEDEITEAF YAYSVLGADE QMWDFEGKEV    50
DEFVVKKLLE RYPMFFKKKI LGKDLRLTPR VPNPSVEKAE AKLLLETLQG 100
ITRAADYARI FYNDSIAPIF EVILPMTTSS AELERVYQLY KKIVGISSEV 150
IHDVTVGEWI GEFYPEEIRI IPLFETKSAL LKSSRIVKEF LKDKDFEHQR 200
VFFARSDPAM NYGLITAVTY VKKALYELAK LEEEMSISLY PIVGVGGPPF 250
RGGMRPDNVD VVLEEYPSVQ TYTIQSSFKF DYPARDVVKA VDKIKSTKRR 300
APTPVDIPEF LTAYEVEYQN QIKLLAPHIR RLASRIPDRR RRKLHIGLFG 350
YARNVNGLAL PRAIKFTASL YSIGLPPELL ALNSVTDKDL ERVSEYYLHV 400
YDDLEFAMKF FSFKVAEEVG LKKLAERVRE FKPDQIQEYV EEAELVFRGE 450
GDVMKLAQMR GFLG 464
Length:464
Mass (Da):53,287
Last modified:September 5, 2012 - v1
Checksum:i7DD6E0511441E7F8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003534 Genomic DNA. Translation: AFK21680.1.
RefSeqiWP_014733206.1. NC_017946.1.
YP_006353755.1. NC_017946.1.

Genome annotation databases

EnsemblBacteriaiAFK21680; AFK21680; Py04_0074.
GeneIDi13021297.
KEGGipys:Py04_0074.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003534 Genomic DNA. Translation: AFK21680.1 .
RefSeqi WP_014733206.1. NC_017946.1.
YP_006353755.1. NC_017946.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFK21680 ; AFK21680 ; Py04_0074 .
GeneIDi 13021297.
KEGGi pys:Py04_0074.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci PSP1183377:GLJ2-77-MONOMER.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of the Hyperthermophilic Archaeon Pyrococcus sp. Strain ST04, Isolated from a Deep-Sea Hydrothermal Sulfide Chimney on the Juan de Fuca Ridge."
    Jung J.H., Lee J.H., Holden J.F., Seo D.H., Shin H., Kim H.Y., Kim W., Ryu S., Park C.S.
    J. Bacteriol. 194:4434-4435(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ST04Imported.

Entry informationi

Entry nameiI3RBS0_9EURY
AccessioniPrimary (citable) accession number: I3RBS0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: September 3, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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