I3RBS0 (I3RBS0_9EURY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
Short name=PEPC HAMAP-Rule MF_01904
Short name=PEPCase HAMAP-Rule MF_01904
EC=4.1.1.31 HAMAP-Rule MF_01904

Gene names

Name:	ppcA HAMAP-Rule MF_01904
ORF Names:	Py04_0074 EMBL AFK21680.1

Organism

Pyrococcus sp. ST04 EMBL AFK21680.1

Taxonomic identifier

1183377 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	464 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904
Cofactor	Magnesium By similarity. HAMAP-Rule MF_01904
Subunit structure	Homotetramer By similarity. HAMAP-Rule MF_01904
Sequence similarities	Belongs to the PEPCase type 2 family. HAMAP-Rule MF_01904

Ontologies

Keywords
Biological process	Carbon dioxide fixation HAMAP-Rule MF_01904
Ligand	Magnesium HAMAP-Rule MF_01904 Pyruvate EMBL AFK21680.1
Molecular function	Lyase HAMAP-Rule MF_01904
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I3RBS0 [UniParc]. Last modified September 5, 2012. Version 1. Checksum: 7DD6E0511441E7F8	FASTA	464	53,287
	10 20 30 40 50 60 MSTQHPDNYS IPFFSHSPVL GGEDEITEAF YAYSVLGADE QMWDFEGKEV DEFVVKKLLE 70 80 90 100 110 120 RYPMFFKKKI LGKDLRLTPR VPNPSVEKAE AKLLLETLQG ITRAADYARI FYNDSIAPIF 130 140 150 160 170 180 EVILPMTTSS AELERVYQLY KKIVGISSEV IHDVTVGEWI GEFYPEEIRI IPLFETKSAL 190 200 210 220 230 240 LKSSRIVKEF LKDKDFEHQR VFFARSDPAM NYGLITAVTY VKKALYELAK LEEEMSISLY 250 260 270 280 290 300 PIVGVGGPPF RGGMRPDNVD VVLEEYPSVQ TYTIQSSFKF DYPARDVVKA VDKIKSTKRR 310 320 330 340 350 360 APTPVDIPEF LTAYEVEYQN QIKLLAPHIR RLASRIPDRR RRKLHIGLFG YARNVNGLAL 370 380 390 400 410 420 PRAIKFTASL YSIGLPPELL ALNSVTDKDL ERVSEYYLHV YDDLEFAMKF FSFKVAEEVG 430 440 450 460 LKKLAERVRE FKPDQIQEYV EEAELVFRGE GDVMKLAQMR GFLG

References

[1]	"Complete Genome Sequence of the Hyperthermophilic Archaeon Pyrococcus sp. Strain ST04, Isolated from a Deep-Sea Hydrothermal Sulfide Chimney on the Juan de Fuca Ridge." Jung J.H., Lee J.H., Holden J.F., Seo D.H., Shin H., Kim H.Y., Kim W., Ryu S., Park C.S. J. Bacteriol. 194:4434-4435(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ST04 EMBL AFK21680.1.
[2]	Jung J.-H., Lee J.-H., Holden J.F., Seo D.-H., Shin H., Kim W., Ryu S., Park C.-S. Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: ST04 EMBL AFK21680.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003534 Genomic DNA. Translation: AFK21680.1.
RefSeq	YP_006353755.1. NC_017946.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFK21680; AFK21680; Py04_0074.
GeneID	13021297.
KEGG	pys:Py04_0074.
Phylogenomic databases
KO	K01595.
Family and domain databases
HAMAP	MF_01904. PEPcase_type2.
InterPro	IPR007566. PEP_COase_arc-type. IPR015813. Pyrv/PenolPyrv_Kinase. [Graphical view]
PIRSF	PIRSF006677. UCP006677. 1 hit.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMs	TIGR02751. PEPCase_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

I3RBS0_9EURY

Accession

Primary (citable) accession number: I3RBS0

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2012
Last sequence update:	September 5, 2012
Last modified:	April 3, 2013
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)