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I3QX48 (I3QX48_CORPS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL AFK16558.1
ORF Names:Cp258_0922 EMBL AFK16558.1
OrganismCorynebacterium pseudotuberculosis 258 [Complete proteome] EMBL AFK16558.1
Taxonomic identifier1168865 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain154 – 358205ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding181 – 23656ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3131Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3251Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3251Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3271Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
I3QX48 [UniParc].

Last modified September 5, 2012. Version 1.
Checksum: BFD7F713C0C482ED

FASTA36339,282
        10         20         30         40         50         60 
MCVVTQKPSP NPRVRVAVVY GGQSSEHSVS CVSAGAIMSH LDPQKYEVFP VGITRDGVWT 

        70         80         90        100        110        120 
VGESDATKLR TVDRVMPEVE FVREVKLSVN PRSAGELRYE DGTLYAQADV IFPALHGRFG 

       130        140        150        160        170        180 
EDGTIQGMFE LSGIPYVGTG VLSSACGMDK EYTKKLLAAE GLPVGKEVIL RGDETLTESD 

       190        200        210        220        230        240 
KQILGLPVFV KPARGGSSIG ISRVIEWEDF DAALTLAREH DTKVIVEAEI KGVEVECGVL 

       250        260        270        280        290        300 
ERADGSLIAS VPAQLEDVDE GEEGFYGFDT KYLDNIVTAT IPAPFDQQTI ALIQSLSLEA 

       310        320        330        340        350        360 
FQALNCRGLS RVDFFVTDQG PVLNEVNTMP GFTPISMYPQ VFEATGIGYA ELLSHLIDQA 


LAQ 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003540 Genomic DNA. Translation: AFK16558.1.
RefSeqYP_006352496.1. NC_017945.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFK16558; AFK16558; Cp258_0922.
GeneID13024009.
KEGGcoe:Cp258_0922.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycCPSE1168865:GLBR-949-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI3QX48_CORPS
AccessionPrimary (citable) accession number: I3QX48
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: February 19, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)