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I3QHR8

- I3QHR8_HUMAN

UniProt

I3QHR8 - I3QHR8_HUMAN

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Protein
Submitted name:

MHC class I antigen

Gene

HLA-B

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: InterPro

GO - Biological processi

  1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
  2. immune response Source: InterPro
  3. positive regulation of T cell mediated cytotoxicity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class I protein complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiI3QHR8.

Expressioni

Gene expression databases

ExpressionAtlasiI3QHR8. baseline.

Structurei

3D structure databases

ProteinModelPortaliI3QHR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Family and domain databases

Gene3Di3.30.500.10. 1 hit.
InterProiIPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

I3QHR8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SHSMRYFYTS VSRPGRGEPR FISVGYVDDT QFVRFDSDAA SPREEPRAPW
60 70 80 90 100
IEQEGPEYWD RNTQIYKAQA QTDRESLRNL RGYYNQSEAG SHTLQSMYGC
110 120 130 140 150
DVGPDGRLLR GHDQYAYDGK DYIALNEDLR SWTAADTAAQ ITQRKWEAAR
160 170 180
EAEQRRAYLE GECVEWLRRY LENGKDKLER A
Length:181
Mass (Da):21,135
Last modified:September 5, 2012 - v1
Checksum:iB437DAAFC018AC90
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei181 – 1811Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ713638 Genomic DNA. Translation: AFK08522.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ713638 Genomic DNA. Translation: AFK08522.1 .

3D structure databases

ProteinModelPortali I3QHR8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi I3QHR8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-B. human.
NextBioi 35533595.

Gene expression databases

ExpressionAtlasi I3QHR8. baseline.

Family and domain databases

Gene3Di 3.30.500.10. 1 hit.
InterProi IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "HLA new alleles found by Histogenetics."
    Cereb N., Yang S.Y.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiI3QHR8_HUMAN
AccessioniPrimary (citable) accession number: I3QHR8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2012
Last sequence update: September 5, 2012
Last modified: October 29, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.