Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Homeobox B8, isoform CRA_a

Gene

HOXB8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi145 – 204HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox B8, isoform CRA_aImported
Submitted name:
Homeobox protein Hox-B8Imported
Gene namesi
Name:HOXB8Imported
ORF Names:hCG_1639847Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:5119. HOXB8.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120068.

Expressioni

Gene expression databases

BgeeiENSG00000120068.
ExpressionAtlasiI3L3R1. baseline and differential.

Structurei

3D structure databases

SMRiI3L3R1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 203Homeobox DNA-bindingInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the Antp homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0489. Eukaryota.
ENOG410ZTBY. LUCA.
GeneTreeiENSGT00760000118945.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR000047. HTH_motif.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
PR00031. HTHREPRESSR.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

I3L3R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH
60 70 80 90 100
PSQIQEFYHG PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ
110 120 130 140 150
DPDLVQYADC KLAAASGLGE EAEGSEQSPS PTQLFPWMRP QAAGRRRGRQ
160 170 180 190 200
TYSRYQTLEL EKEFLFNPYL TRKRRIEVSH ALGLTERQVK IWFQNRRMKW
210 220 230 240
KKENNKDKFP SSKCEQEELE KQKLERAPEA ADEGDAQKGD KK
Length:242
Mass (Da):27,503
Last modified:July 11, 2012 - v1
Checksum:i93A47C2FF0A121C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103702 Genomic DNA. No translation available.
CH471109 Genomic DNA. Translation: EAW94723.1.
RefSeqiXP_005257343.1. XM_005257286.2.
UniGeneiHs.514292.

Genome annotation databases

EnsembliENST00000576562; ENSP00000460659; ENSG00000120068.
GeneIDi3218.
UCSCiuc060gwl.1. human.

Similar proteinsi

Entry informationi

Entry nameiI3L3R1_HUMAN
AccessioniPrimary (citable) accession number: I3L3R1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported