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Protein
Submitted name:

Homeobox B8, isoform CRA_a

Gene

HOXB8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi145 – 204HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox B8, isoform CRA_aImported
Submitted name:
Homeobox protein Hox-B8Imported
Gene namesi
Name:HOXB8Imported
ORF Names:hCG_1639847Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000120068.6
HGNCiHGNC:5119 HOXB8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120068

PTM / Processingi

Proteomic databases

PeptideAtlasiI3L3R1
PRIDEiI3L3R1

Expressioni

Gene expression databases

BgeeiENSG00000120068
ExpressionAtlasiI3L3R1 baseline and differential

Structurei

3D structure databases

SMRiI3L3R1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 203HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the Antp homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0489 Eukaryota
ENOG410ZTBY LUCA
GeneTreeiENSGT00910000143983

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR000047 HTH_motif
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00024 HOMEOBOX
PR00031 HTHREPRESSR
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

I3L3R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH
60 70 80 90 100
PSQIQEFYHG PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ
110 120 130 140 150
DPDLVQYADC KLAAASGLGE EAEGSEQSPS PTQLFPWMRP QAAGRRRGRQ
160 170 180 190 200
TYSRYQTLEL EKEFLFNPYL TRKRRIEVSH ALGLTERQVK IWFQNRRMKW
210 220 230 240
KKENNKDKFP SSKCEQEELE KQKLERAPEA ADEGDAQKGD KK
Length:242
Mass (Da):27,503
Last modified:July 11, 2012 - v1
Checksum:i93A47C2FF0A121C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103702 Genomic DNA No translation available.
CH471109 Genomic DNA Translation: EAW94723.1
RefSeqiXP_005257343.1, XM_005257286.2
UniGeneiHs.514292

Genome annotation databases

EnsembliENST00000576562; ENSP00000460659; ENSG00000120068
GeneIDi3218
UCSCiuc060gwl.1 human

Similar proteinsi

Entry informationi

Entry nameiI3L3R1_HUMAN
AccessioniPrimary (citable) accession number: I3L3R1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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