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Protein
Submitted name:

CREB-binding protein

Gene

CREBBP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CREB-binding proteinImported
Gene namesi
Name:CREBBPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000005339.13.
HGNCiHGNC:2348. CREBBP.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000005339.

PTM / Processingi

Proteomic databases

PaxDbiI3L3I5.
PeptideAtlasiI3L3I5.
PRIDEiI3L3I5.

Expressioni

Gene expression databases

BgeeiENSG00000005339.
ExpressionAtlasiI3L3I5. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 196CBP/p300-type HATInterPro annotationAdd BLAST105

Phylogenomic databases

eggNOGiKOG1778. Eukaryota.
COG5076. LUCA.
GeneTreeiENSGT00760000119206.

Family and domain databases

CDDicd15802. RING_CBP-p300. 1 hit.
Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR031162. CBP_P300_HAT.
IPR013178. Histone_AcTrfase_Rtt109/CBP.
IPR010303. RING_CBP-p300.
IPR011011. Znf_FYVE_PHD.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF08214. HAT_KAT11. 1 hit.
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiView protein in PROSITE
PS51727. CBP_P300_HAT. 1 hit.

Sequencei

Sequence statusi: Fragment.

I3L3I5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XRYHFCEKCF TEIQGENVTL GDDPSQPQTT ISKDQFEKKK NDTLDPEPFV
60 70 80 90 100
DCKECGRKMH QICVLHYDII WPSGFVCDNC LKKTGRPRKE NKFSAKRLQT
110 120 130 140 150
TRLGNHLEDR VNKFLRRQNH PEAGEVFVRV VASSDKTVEV KPGMKSRFVD
160 170 180 190
SGEMSESFPY RTKALFAFEE IDGVDVCFFG MHVQEYGSDC PPPNTR
Length:196
Mass (Da):22,589
Last modified:February 17, 2016 - v2
Checksum:i8222BCED8A3D2182
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004509 Genomic DNA. No translation available.
AC004651 Genomic DNA. No translation available.
AC006111 Genomic DNA. No translation available.
AC007151 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000573517; ENSP00000460474; ENSG00000005339.
UCSCiuc059qbs.1. human.

Entry informationi

Entry nameiI3L3I5_HUMAN
AccessioniPrimary (citable) accession number: I3L3I5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: February 17, 2016
Last modified: September 27, 2017
This is version 37 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported