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Protein
Submitted name:

Segment polarity protein dishevelled homolog DVL-2

Gene

DVL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processWnt signaling pathwayPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Segment polarity protein dishevelled homolog DVL-2Imported
Gene namesi
Name:DVL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000004975.11.
HGNCiHGNC:3086. DVL2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000004975.

PTM / Processingi

Proteomic databases

MaxQBiI3L2W9.
PaxDbiI3L2W9.
PeptideAtlasiI3L2W9.
PRIDEiI3L2W9.

Expressioni

Gene expression databases

BgeeiENSG00000004975.
ExpressionAtlasiI3L2W9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliI3L2W9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 93DIXInterPro annotationAdd BLAST83
Domaini263 – 335PDZInterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG3571. Eukaryota.
ENOG410Y5G4. LUCA.
GeneTreeiENSGT00390000013552.

Family and domain databases

InterProiView protein in InterPro
IPR003351. Dishevelled_protein_dom.
IPR001158. DIX.
IPR015506. Dsh/Dvl-rel.
IPR008341. DVL2.
IPR001478. PDZ.
IPR029071. Ubiquitin-rel_dom.
PANTHERiPTHR10878. PTHR10878. 1 hit.
PTHR10878:SF31. PTHR10878:SF31. 1 hit.
PfamiView protein in Pfam
PF02377. Dishevelled. 1 hit.
PF00778. DIX. 1 hit.
PF00595. PDZ. 1 hit.
SMARTiView protein in SMART
SM00021. DAX. 1 hit.
SM00228. PDZ. 1 hit.
SUPFAMiSSF50156. SSF50156. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiView protein in PROSITE
PS50841. DIX. 1 hit.
PS50106. PDZ. 1 hit.

Sequencei

Sequence statusi: Fragment.

I3L2W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSSTGGGG VGETKVIYHL DEEETPYLVK IPVPAERITL GDFKSVLQRP
60 70 80 90 100
AGAKYFFKSM DQDFGVVKEE ISDDNARLPC FNGRVVSWLV SSDNPQPEMA
110 120 130 140 150
PPVHEPRAEL APPAPPLPPL PPERTSGIGD SRPPSFHPNV SSSHENLEPE
160 170 180 190 200
TETESVVSLR RERPRRRDST GGHRTGGPSR LERHLAGYES SSTLMTSELE
210 220 230 240 250
STSLGDSDEE DTMSRFSSST EQSSASRLLK RHRRRRKQRP PRLERTSSFS
260 270 280 290 300
SVTDSTMSLN IITVTLNMEK YNFLGISIVG QSNERGDGGI YIGSIMKGGA
310 320 330 340 350
VAADGRIEPG DMLLQVNDMN FENMSNDDAV RVLRDIVHKP GPIVLTVAKC
360
WDPSPQAYFT LPR
Length:363
Mass (Da):39,918
Last modified:July 11, 2012 - v1
Checksum:iB336D6CBDAFB0EBA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei363Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120057 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000575756; ENSP00000459991; ENSG00000004975.
UCSCiuc060aka.1. human.

Similar proteinsi

Entry informationi

Entry nameiI3L2W9_HUMAN
AccessioniPrimary (citable) accession number: I3L2W9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 27, 2017
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported