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Protein
Submitted name:

Uncharacterized protein

Gene

glur2a

Organism
Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:glur2aImported
OrganismiOreochromis niloticus (Nile tilapia) (Tilapia nilotica)Imported
Taxonomic identifieri8128 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaCichlomorphaeCichliformesCichlidaeAfrican cichlidsPseudocrenilabrinaeOreochrominiOreochromis
Proteomesi
  • UP000005207 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei546 – 568HelicalSequence analysisAdd BLAST23
Transmembranei629 – 651HelicalSequence analysisAdd BLAST23
Transmembranei819 – 841HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500367465029 – 895Sequence analysisAdd BLAST867

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini419 – 794PBPeInterPro annotationAdd BLAST376
Domaini429 – 494Lig_chan-Glu_bdInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1054. Eukaryota.
ENOG410XPSH. LUCA.
GeneTreeiENSGT00760000118920.

Family and domain databases

InterProiView protein in InterPro
IPR001828. ANF_lig-bd_rcpt.
IPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
PfamiView protein in Pfam
PF01094. ANF_receptor. 1 hit.
PF00060. Lig_chan. 1 hit.
PF10613. Lig_chan-Glu_bd. 1 hit.
PRINTSiPR00177. NMDARECEPTOR.
SMARTiView protein in SMART
SM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

I3KGJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLWCCARILN TTMKLLFLVA LLWRGALCGS PSVQIGGLFP RGADQEYSAF
60 70 80 90 100
RVGMVQFGMA DFRLTPHIDN LEVANSFAVT NCFCSQFSRG VYAIFGFYDK
110 120 130 140 150
KSVNTITSFC ETLHVSFITP SFPAEGMNQF VLQMRPDIKG PLVSLVEYYK
160 170 180 190 200
WEKFAYLYDS DRGLSTLQVI LDTAAEKKWV VTAINVGNLK DERKDEAYRS
210 220 230 240 250
LFQDLEIRKE RRIILDCEQD KVKDIMEQVI TIGRHVKGYH YIIANLGFVD
260 270 280 290 300
GDLSKIQYGG ANVSGFQIVD FDDPVVAKFD QRWEALEEKE YPGADTRIRY
310 320 330 340 350
TSALTYDAVH VMTEAFRFLH KQRIDISRRG NSGDCLANPA VPWAQGVEIE
360 370 380 390 400
RALKQVHVDG LTGNIQFDQY GKRINYSVTI MELKNNGPVK IGYWNEVDKM
410 420 430 440 450
VLTKSDLYPN DTMGMENKTV IVTTILEAPY VMLKKNAELF QDNDRYEGYC
460 470 480 490 500
VDLAAEIAKH CGIRYQLRIV GDGKYGARDA ETKIWNGMVG ELVYGKADIA
510 520 530 540 550
IAPLTITLVR EEVIDFSKPF MSLGISIMIK KPQKSKPGVF SFLDPLAYEI
560 570 580 590 600
WMCIVFAYIG VSVVLFLVSR FSPYEWTLEE PEDGALPLTT ESTNEFGIFN
610 620 630 640 650
SLWFSLGAFM RQGCDISPRS LSGRIVGGVW WFFTLIIISS YTANLAAFLT
660 670 680 690 700
VERMVSPIES AEDLAKQTEI AYGTLDSGST KEFFRRSKIA LFDKMWQYMK
710 720 730 740 750
NAEPSVFVKK TSEGVQRVRK SKGKYAYLLE STMNEYIEQR KPCDTMKVGG
760 770 780 790 800
NLDSKGYGIA TPKGSPLRNA VNLAVLKLNE QGLLDKLKNK WWYDKGECGS
810 820 830 840 850
GGGESKEKTS ALSLSNVAGV FYILVGGLGL AMMVALVEFC YKSRAEAKKM
860 870 880 890
KMKFTDAMRS KARLSITGST SENGRVPVAY LRPGLPMSLS MTDLS
Length:895
Mass (Da):100,617
Last modified:July 11, 2012 - v1
Checksum:i02C200B7714109E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AERX01029410 Genomic DNA. No translation available.
AERX01029411 Genomic DNA. No translation available.
AERX01029412 Genomic DNA. No translation available.
AERX01029413 Genomic DNA. No translation available.
AERX01029414 Genomic DNA. No translation available.
AERX01029415 Genomic DNA. No translation available.
AERX01029416 Genomic DNA. No translation available.
AERX01029417 Genomic DNA. No translation available.
AERX01029418 Genomic DNA. No translation available.
AERX01029419 Genomic DNA. No translation available.
RefSeqiXP_005457669.1. XM_005457612.2.
UniGeneiOni.44249.

Genome annotation databases

EnsembliENSONIT00000020258; ENSONIP00000020241; ENSONIG00000016067.
GeneIDi100534587.

Similar proteinsi

Entry informationi

Entry nameiI3KGJ6_ORENI
AccessioniPrimary (citable) accession number: I3KGJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: July 5, 2017
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported