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Protein
Submitted name:

Nuclear receptor subfamily 3, group C, member 2

Gene

nr3c2

Organism
Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi614 – 689Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3, group C, member 2Imported
Gene namesi
Name:nr3c2Imported
OrganismiOreochromis niloticus (Nile tilapia) (Tilapia nilotica)Imported
Taxonomic identifieri8128 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaCichlomorphaeCichliformesCichlidaeAfrican cichlidsPseudocrenilabrinaeOreochrominiOreochromis
Proteomesi
  • UP000005207 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi8128.ENSONIP00000012611.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini614 – 689Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118887.
InParanoidiI3JUR6.
OMAiSKICLVC.
OrthoDBiEOG091G0166.
TreeFamiTF106510.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

I3JUR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKRYQSFF DGKDTENRWP QVPGTMEYCC STEDSSLTGS DILMDIVNVN
60 70 80 90 100
CPAGSPATDC KDNNTKKQEQ PMLQLSQNQP FVLPHFNNSL LGHKQEMDSK
110 120 130 140 150
ELSKTVAESM GLYMNAAREA DFAFNQQGAN TSPGKLYPAC GRPLEENQCG
160 170 180 190 200
PTKSPKLKPF GFQQPSATPR ECTAGTPVSS ASMLASSLSC SPQTSSAISS
210 220 230 240 250
PGGSNNMVSS TTSPPTCFAP LCSSVSSPVS QTSCAATLAN IKRRNSVTCS
260 270 280 290 300
PVESSTVGSP PLTSPLNVMR SPMSSPQSMS SVRSPPSCST TCNIRSSVSS
310 320 330 340 350
PTAGSCSGNT TNNCNTAMPS ISSPATAGTM TVSSPQNPSS AGFPVSSPAD
360 370 380 390 400
GLGLVQNDTN SPEAAGLTRE TDFKNFEFPK VEMVDGEVFN VGLDQMGMVK
410 420 430 440 450
YIKNEPGTDF RSMCLGSSKC NASSTPFITQ IKSEPNKSEG CMNHQPYGEQ
460 470 480 490 500
SPSIGLFPAS ETTYLSLRNN IDEYSLSGIL GPPVSSVNGN YESDVFSNNV
510 520 530 540 550
LSKGVKQEST DGSYYQENNS MSTSAIVGVN SGGHSFHYQI GAQGTMSFTR
560 570 580 590 600
HDMRDQTNPL LNLISPVTAL MESWKSHPGM SQGSLAARGE GYPGQNCISD
610 620 630 640 650
GMSSSPLRQP SSTAKVCLVC GDEASGCHYG VVTCGSCKVF FKRAVEGQHN
660 670 680 690 700
YLCAGRNDCI IDKIRRKNCP ACRVRKCLQA GMNLGARKSK KLKLKGVSED
710 720 730 740 750
LQGSKDGQTA TGGAGGYLSS EKELNASAAN ALVPHRPGVV TPFLPPSICS
760 770 780 790 800
VLELIEPEEV YSGYDNTQPD TTDHLLSSLN RLAGKQMVRM VKWAKVLPGF
810 820 830 840 850
RSLPIEDQIT LIQYSWMCLS SFCLSWRSYK HTNGQMLYFA PDLIFNEERM
860 870 880 890 900
QQSAMYDLCL GMRQVSQEFV RLQLTYDEFL SMKVLLLLST VPKEGLKNQA
910 920 930 940 950
AFEEMRVNYI KELRRSVGKA TNNSGQTWQR FFQLTKLLDA MHDLVGNLLD
960 970 980 990
FCFYTFRESQ ALKVEFPEML VEIISDQIPK VESGLTHTIY FHKK
Length:994
Mass (Da):107,815
Last modified:July 11, 2012 - v1
Checksum:i039A1E5944EAA3F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AERX01022612 Genomic DNA. No translation available.
AERX01022613 Genomic DNA. No translation available.
RefSeqiXP_003449722.1. XM_003449674.4.

Genome annotation databases

EnsembliENSONIT00000012621; ENSONIP00000012611; ENSONIG00000010029.
GeneIDi100712208.

Similar proteinsi

Entry informationi

Entry nameiI3JUR6_ORENI
AccessioniPrimary (citable) accession number: I3JUR6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 27, 2017
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported