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Protein

DEAD-box ATP-dependent RNA helicase CshA

Gene

cshA

Organism
Bacillus sp. 5B6
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase, RNA-bindingUniRule annotation
Biological processStress responseUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DEAD-box ATP-dependent RNA helicase CshAUniRule annotation (EC:3.6.4.13UniRule annotation)
Gene namesi
Name:cshAUniRule annotation
ORF Names:MY7_0314Imported
OrganismiBacillus sp. 5B6Imported
Taxonomic identifieri1127743 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000005799 Componenti: Unassembled WGS sequence

Subcellular locationi

I2HMR8:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Oligomerizes, may be a member of the RNA degradosome.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI2HMR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 54Q_MOTIFInterPro annotationAdd BLAST29
Domaini57 – 227Helicase ATP-bindingInterPro annotationAdd BLAST171
Domaini238 – 398Helicase C-terminalInterPro annotationAdd BLAST161

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi26 – 54Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. CshA subfamily.UniRule annotation

Family and domain databases

CDDicd00079. HELICc. 1 hit.
HAMAPiMF_01493. DEAD_helicase_CshA. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR030880. DEAD_helicase_CshA.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

I2HMR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGRFLVVNH DITETAIRRS LNNLTITFQD FQLSSDLMKS INRMGFEEAT
60 70 80 90 100
PIQAQTIPLG LLNKDVIGQA QTGTGKTAAF GIPLVEKMNP ESPNIQAIVI
110 120 130 140 150
APTRELAIQV SEELYKIGQD KRAKVLPIYG GQDIGRQIRA LKKNPHIIVG
160 170 180 190 200
TPGRLLDHIN RRTIRLNNVN TVVMDEADEM LNMGFIDDIE SILSNVPSDH
210 220 230 240 250
QTLLFSATMP APIKRIAERF MTEPEHVKVK AKEMTVSNIQ QFYLEVQERK
260 270 280 290 300
KFDTLTRLLD IQSPELAIVF GRTKRRVDEL AEALNLRGYA AEGIHGDLTQ
310 320 330 340 350
AKRMVALRKF KEGAIEVLVA TDVAARGLDI SGVTHVYNFD VPQDPESYVH
360 370 380 390 400
RIGRTGRAGK TGMAMTFITP REKSMLRAIE QTTKRKMDRM KEPTLDEALE
410 420 430 440 450
GQQQVTVDRL RTAISENNLN FYMTAAAELL EDHDAVTVVA AAIKMATKEP
460 470 480 490 500
DSTPVRLTDE APMVSKRYKN QRTSKRRDGQ GGGYRGGKGK TNNRSSYDKK
510
RSSDRRSSGD RRQKKSY
Length:517
Mass (Da):57,991
Last modified:July 11, 2012 - v1
Checksum:iD2CC5766AE56DDCD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJST01000001 Genomic DNA. Translation: EIF12027.1.

Genome annotation databases

EnsemblBacteriaiEIF12027; EIF12027; MY7_0314.
PATRICifig|1127743.3.peg.308.

Similar proteinsi

Entry informationi

Entry nameiI2HMR8_9BACI
AccessioniPrimary (citable) accession number: I2HMR8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: October 25, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported