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I2FA87 (I2FA87_HELCP) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length348 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2571Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1221Substrate By similarity HAMAP-Rule MF_01201
Binding site3031Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I2FA87 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: 292E4CB5404E63DD

FASTA34838,734
        10         20         30         40         50         60 
MAEIILDSKA YKHNLNLIHS HINSHNKSNV EIAAVLKDNA YGHGLKEMAT IAAEYGIKSV 

        70         80         90        100        110        120 
FVKNYNEAIQ IYKFFPQVTA FYGMPQGDFA KNIAFVIHDE KHISALPQGT KVELKVNVGM 

       130        140        150        160        170        180 
NRNGIEPSEL ESFIQAILQK KLELIGVFSH NGYGDDLDSV FFHTQSNFAK LKQEVLHLSQ 

       190        200        210        220        230        240 
KYGFAPPRFH SLSTSGAIRV ASEGGITDDL VRIGIGAYGY LDVSFENPIS DKLQKVASLY 

       250        260        270        280        290        300 
ADRVSTRFLD KGERIGYSGC TTLNSPQVVS TYDIGYGDGF FRVNENHKVY IANGLQILPR 

       310        320        330        340 
SSMDCFSCFC DEPRICVFND VTHLAKAFGT ISYEILTHLS PSIKRTII 

« Hide

References

[1]"Complete genome sequence of Helicobacter cinaedi strain PAGU611 isolated from human bacteremia."
Goto T., Ogura Y., Hirakawa H., Tomida J., Morita Y., Akaike T., Hayashi T., Kawamura Y.
Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PAGU611.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP012344 Genomic DNA. Translation: BAM11775.1.
RefSeqYP_006234886.1. NC_017761.1.

3D structure databases

ProteinModelPortalI2FA87.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAM11775; BAM11775; HCN_0483.
GeneID12763736.
KEGGhcp:HCN_0483.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMARIGYSGC.

Enzyme and pathway databases

BioCycHCIN1172562:GLDZ-497-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI2FA87_HELCP
AccessionPrimary (citable) accession number: I2FA87
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: July 9, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)