I2F2J5 (I2F2J5_9THEM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

ORF Names:

Theba_0420 EMBL AFK06148.1

Organism

Mesotoga prima MesG1.Ag.4.2 EMBL AFK06148.1

Taxonomic identifier

660470 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Thermotogae › Thermotogae › Thermotogales › Thermotogaceae › Mesotoga › Mesotoga prima

Protein attributes

Sequence length	369 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I2F2J5 [UniParc]. Last modified July 11, 2012. Version 1. Checksum: 2A4078CCB13646FD	FASTA	369	40,779
	10 20 30 40 50 60 MNSRKTFALI DLSAYRQNLV YLSGKASPAK LMVVVKADAY GHGAVELSKV AQESGVDRLA 70 80 90 100 110 120 VAFLEEGIKI RQSGISLPIL VLNYVEKKEI PTAKEFSLTL SLSSFAQLEN IIGLNKQLPD 130 140 150 160 170 180 FQLVVDTGMR RLGLEWEESI ELYNSAVRKG INITGAYTHF ATADEKGSGF VLEQREAFGR 190 200 210 220 230 240 FLHGLGQRRN RHFETHISNS AGTIYFDNSD FSYVRAGIAT YGLQPSKETD ENLKPVLSWV 250 260 270 280 290 300 SCVSFVKRIR TGYSVSYGRT FVADRDMLVA TIPVGYADGY NRLLSNRGYV IISGKRCKVL 310 320 330 340 350 360 GRVCMDQFVV DISHIEKPVS IGDEVVIVGT QEGESISAEE IADLCGTINY EVVCSISSRV PRVYKKGVN

References

[1]

"Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date." Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C., Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N., Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L. Genome Biol. Evol. 4:700-708(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: MesG1.Ag.4.2 EMBL AFK06148.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003532 Genomic DNA. Translation: AFK06148.1.
RefSeq	YP_006345391.1. NC_017934.1.
3D structure databases
ProteinModelPortal	I2F2J5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFK06148; AFK06148; Theba_0420.
GeneID	13029608.
KEGG	mpg:Theba_0420.
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I2F2J5_9THEM

Accession

Primary (citable) accession number: I2F2J5

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2012
Last sequence update:	July 11, 2012
Last modified:	April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)