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I2F2J5 (I2F2J5_9THEM) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site361Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2571Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1311Substrate By similarity HAMAP-Rule MF_01201
Binding site3051Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue361N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I2F2J5 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: 2A4078CCB13646FD

FASTA36940,779
        10         20         30         40         50         60 
MNSRKTFALI DLSAYRQNLV YLSGKASPAK LMVVVKADAY GHGAVELSKV AQESGVDRLA 

        70         80         90        100        110        120 
VAFLEEGIKI RQSGISLPIL VLNYVEKKEI PTAKEFSLTL SLSSFAQLEN IIGLNKQLPD 

       130        140        150        160        170        180 
FQLVVDTGMR RLGLEWEESI ELYNSAVRKG INITGAYTHF ATADEKGSGF VLEQREAFGR 

       190        200        210        220        230        240 
FLHGLGQRRN RHFETHISNS AGTIYFDNSD FSYVRAGIAT YGLQPSKETD ENLKPVLSWV 

       250        260        270        280        290        300 
SCVSFVKRIR TGYSVSYGRT FVADRDMLVA TIPVGYADGY NRLLSNRGYV IISGKRCKVL 

       310        320        330        340        350        360 
GRVCMDQFVV DISHIEKPVS IGDEVVIVGT QEGESISAEE IADLCGTINY EVVCSISSRV 


PRVYKKGVN 

« Hide

References

[1]"Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date."
Zhaxybayeva O., Swithers K.S., Foght J., Green A.G., Bruce D., Detter C., Han S., Teshima H., Han J., Woyke T., Pitluck S., Nolan M., Ivanova N., Pati A., Land M.L., Dlutek M., Doolittle W.F., Noll K.M., Nesbo C.L.
Genome Biol. Evol. 4:700-708(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MesG1.Ag.4.2 EMBL AFK06148.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003532 Genomic DNA. Translation: AFK06148.1.
RefSeqYP_006345391.1. NC_017934.1.

3D structure databases

ProteinModelPortalI2F2J5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFK06148; AFK06148; Theba_0420.
GeneID13029608.
KEGGmpg:Theba_0420.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycMPRI660470:GLGB-420-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI2F2J5_9THEM
AccessionPrimary (citable) accession number: I2F2J5
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: February 19, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)