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I2EY86

- I2EY86_EMTOG

UniProt

I2EY86 - I2EY86_EMTOG

Protein
Submitted name:

D-alanine--D-alanine ligase domain protein

Gene

Emtol_3511

Organism
Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (11 Jul 2012)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligase domain proteinImported
    Gene namesi
    Ordered Locus Names:Emtol_3511Imported
    OrganismiEmticicia oligotrophica (strain DSM 17448 / GPTSA100-15)Imported
    Taxonomic identifieri929562 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeEmticicia
    ProteomesiUP000002875: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    KOiK01921.
    OMAiQGLLEWY.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 2 hits.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I2EY86-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPCYFLNGTL LAEPNCEQNL IMTNKIRVGV FFGGQARERE ISYLGGKTAF    50
    EHIDKAIFEP VPIFVDSLGH FIQINPELLY EDSIRDFFPS KNLNRGFRVY 100
    IESLGELNET QLYKLIYKVG KQVQPTDFSN LMDFAFVIMH GPQAEDGAIQ 150
    GLLEWYGIPY MGPGLMGSAV GIDKPMQNKL LSLVTGQKKK MVTFTRDEWQ 200
    VADRSKLFTD LINNIGFPFV VKAPHQGSSI GVAIVRKRSL EEFTKAIQQC 250
    FFETTFLKRE WEKMTDRQKR HLMEKTSNLD EGIGFPLYVN GKILHHPAEL 300
    MEELDALLFT LDSVTAISAN AEDHVMIEEF VVGQEFSCGV IQHDDGTALA 350
    LPPTEIYGEI QTFDFKSKYK SNVTKKRIPV ETSIENLNKI HDNLLKAFNN 400
    LGFSVVTRID GFLTPDSRVL LHDPNTLPGM SPASLIFKQM AEIGLTVTQS 450
    ITYFVRQSIR ERIRSGKNTV ALRNLLEKID SLIEGRVSAH RKKVAIIFGE 500
    TDEEYKTAQR KLGEYASSVA YEPVCVCAAR NGQMYKIPVN LMFKADIQDF 550
    GQNIGKSKHP FIAEIIRKAE KITNKYAGSF DTQVKKLSET ELAESVQFIF 600
    QCDSDTLVEL 610
    Length:610
    Mass (Da):68,960
    Last modified:July 11, 2012 - v1
    Checksum:i9DDBBA6E97192CF2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002961 Genomic DNA. Translation: AFK04639.1.
    RefSeqiWP_015030328.1. NC_018748.1.
    YP_006874666.1. NC_018748.1.

    Genome annotation databases

    EnsemblBacteriaiAFK04639; AFK04639; Emtol_3511.
    GeneIDi13813389.
    KEGGieol:Emtol_3511.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002961 Genomic DNA. Translation: AFK04639.1 .
    RefSeqi WP_015030328.1. NC_018748.1.
    YP_006874666.1. NC_018748.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFK04639 ; AFK04639 ; Emtol_3511 .
    GeneIDi 13813389.
    KEGGi eol:Emtol_3511.

    Phylogenomic databases

    KOi K01921.
    OMAi QGLLEWY.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 2 hits.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 17448 / GPTSA100-15Imported.

    Entry informationi

    Entry nameiI2EY86_EMTOG
    AccessioniPrimary (citable) accession number: I2EY86
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 11, 2012
    Last sequence update: July 11, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3