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I2EY86

- I2EY86_EMTOG

UniProt

I2EY86 - I2EY86_EMTOG

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Protein
Submitted name:

D-alanine--D-alanine ligase domain protein

Gene
Emtol_3511
Organism
Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation By similarity.SAAS annotations

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotations

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationsImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotations, Peptidoglycan synthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, MagnesiumSAAS annotations, ManganeseSAAS annotations, Metal-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligase domain proteinImported
Gene namesi
Ordered Locus Names:Emtol_3511Imported
OrganismiEmticicia oligotrophica (strain DSM 17448 / GPTSA100-15)Imported
Taxonomic identifieri929562 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeEmticicia
ProteomesiUP000002875: Chromosome

Subcellular locationi

Cytoplasm By similarity SAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

KOiK01921.
OMAiQGLLEWY.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 2 hits.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I2EY86-1 [UniParc]FASTAAdd to Basket

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MPCYFLNGTL LAEPNCEQNL IMTNKIRVGV FFGGQARERE ISYLGGKTAF    50
EHIDKAIFEP VPIFVDSLGH FIQINPELLY EDSIRDFFPS KNLNRGFRVY 100
IESLGELNET QLYKLIYKVG KQVQPTDFSN LMDFAFVIMH GPQAEDGAIQ 150
GLLEWYGIPY MGPGLMGSAV GIDKPMQNKL LSLVTGQKKK MVTFTRDEWQ 200
VADRSKLFTD LINNIGFPFV VKAPHQGSSI GVAIVRKRSL EEFTKAIQQC 250
FFETTFLKRE WEKMTDRQKR HLMEKTSNLD EGIGFPLYVN GKILHHPAEL 300
MEELDALLFT LDSVTAISAN AEDHVMIEEF VVGQEFSCGV IQHDDGTALA 350
LPPTEIYGEI QTFDFKSKYK SNVTKKRIPV ETSIENLNKI HDNLLKAFNN 400
LGFSVVTRID GFLTPDSRVL LHDPNTLPGM SPASLIFKQM AEIGLTVTQS 450
ITYFVRQSIR ERIRSGKNTV ALRNLLEKID SLIEGRVSAH RKKVAIIFGE 500
TDEEYKTAQR KLGEYASSVA YEPVCVCAAR NGQMYKIPVN LMFKADIQDF 550
GQNIGKSKHP FIAEIIRKAE KITNKYAGSF DTQVKKLSET ELAESVQFIF 600
QCDSDTLVEL 610
Length:610
Mass (Da):68,960
Last modified:July 11, 2012 - v1
Checksum:i9DDBBA6E97192CF2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002961 Genomic DNA. Translation: AFK04639.1.
RefSeqiWP_015030328.1. NC_018748.1.
YP_006874666.1. NC_018748.1.

Genome annotation databases

EnsemblBacteriaiAFK04639; AFK04639; Emtol_3511.
GeneIDi13813389.
KEGGieol:Emtol_3511.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002961 Genomic DNA. Translation: AFK04639.1 .
RefSeqi WP_015030328.1. NC_018748.1.
YP_006874666.1. NC_018748.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFK04639 ; AFK04639 ; Emtol_3511 .
GeneIDi 13813389.
KEGGi eol:Emtol_3511.

Phylogenomic databases

KOi K01921.
OMAi QGLLEWY.

Enzyme and pathway databases

UniPathwayi UPA00219 .

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 2 hits.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17448 / GPTSA100-15.

Entry informationi

Entry nameiI2EY86_EMTOG
AccessioniPrimary (citable) accession number: I2EY86
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 3, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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