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Protein

Beta-galactosidase

Gene

MYA_3481

Organism
Burkholderia sp. KJ006
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei103 – 1031SubstrateUniRule annotation
Binding sitei141 – 1411SubstrateUniRule annotation
Active sitei142 – 1421Proton donorUniRule annotation
Active sitei313 – 3131NucleophileUniRule annotation
Binding sitei321 – 3211SubstrateUniRule annotation

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

BioCyciBSP416344:GL9Z-3558-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Gene namesi
ORF Names:MYA_3481Imported
OrganismiBurkholderia sp. KJ006Imported
Taxonomic identifieri416344 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000010108 Componenti: Chromosome 2

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 42 family.UniRule annotation

Phylogenomic databases

KOiK12308.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

I2DT64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLGVCYYPE HWPESMWADD ARRMKALGIV QVRIGEFAWS RIEPSPGEYA
60 70 80 90 100
WGWLDRAIDA LGAAGLEIVM CTPTATPPKW LVDRHPDILA IGADGLPRKF
110 120 130 140 150
GSRRHYDFSS PTYLEASRRI CTAVAERYGR HPAVRYWQTD NELGCHQTVV
160 170 180 190 200
SYSPAALLRF RAWLKARYGT IDALNRAWGT VFWSMEYRHF DEVDAPVGTV
210 220 230 240 250
TEAHPSHRLD YRRFASDELA RYHRMQVDVI RAHSPGRPVA HNFMQLFTEF
260 270 280 290 300
DHYAVARDLD VATWDSYPLG ALEELWFAPD VKARWLRTGH PDFASFNHDL
310 320 330 340 350
YRGMSKQPFW VMEQQPGPVN WAHWNPAPLP GMVRLWSWEA FAHGAGCVSY
360 370 380 390 400
FRWRQAPFAQ EQMHAGLHTP DDRLDEGGRE AQRVAGEIAA VLDADADGAV
410 420 430 440 450
RAPVALVFDY EAKWLLEVQP QGADFHYPRF AFEYYSALRA LGLDVDIVSA
460 470 480 490 500
HAPLDGYRLV VVPPLPVVPD DFAARLAASG AHAVFGPRTG SKTVDLQIPP
510 520 530 540 550
ALPPGPLASL LPLRVWRVES LRPNVTERID GALRDGSPLS GDARHWRDLV
560 570 580 590 600
ELHDDARSVV HARFADGHPA WVSHGAFHYW AALFDDATTL RGFADVAAEA
610 620 630 640 650
GLTPTPLGDD VRVSRRGGLT YVFNYGSTPH TIDAVAPSAF VVGAAQVEPQ

GVAVYRSRP
Length:659
Mass (Da):73,771
Last modified:July 10, 2012 - v1
Checksum:iDC105922D156155C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003515 Genomic DNA. Translation: AFJ87840.1.
RefSeqiWP_014724277.1. NC_017921.1.
YP_006334571.1. NC_017921.1.

Genome annotation databases

EnsemblBacteriaiAFJ87840; AFJ87840; MYA_3481.
KEGGibuk:MYA_3481.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003515 Genomic DNA. Translation: AFJ87840.1.
RefSeqiWP_014724277.1. NC_017921.1.
YP_006334571.1. NC_017921.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFJ87840; AFJ87840; MYA_3481.
KEGGibuk:MYA_3481.

Phylogenomic databases

KOiK12308.

Enzyme and pathway databases

BioCyciBSP416344:GL9Z-3558-MONOMER.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete Genome Sequence of the Endophytic Bacterium Burkholderia sp. Strain KJ006."
    Kwak M.J., Song J.Y., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K., Lee C.H., Yu D.S., Park S.H., Kim J.F.
    J. Bacteriol. 194:4432-4433(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KJ006Imported.

Entry informationi

Entry nameiI2DT64_9BURK
AccessioniPrimary (citable) accession number: I2DT64
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2012
Last sequence update: July 10, 2012
Last modified: March 31, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.