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I2DPS2

- I2DPS2_9BURK

UniProt

I2DPS2 - I2DPS2_9BURK

Protein
Submitted name:

Isocitrate dehydrogenase, Monomeric isocitrate dehydrogenase

Gene

MYA_2288

Organism
Burkholderia sp. KJ006
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (11 Jul 2012)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei146 – 1461SubstrateUniRule annotation
    Sitei256 – 2561Critical for catalysisUniRule annotation
    Metal bindingi351 – 3511Magnesium or manganese
    Sitei421 – 4211Critical for catalysisUniRule annotation
    Binding sitei548 – 5481SubstrateUniRule annotation
    Metal bindingi549 – 5491Magnesium or manganese
    Metal bindingi553 – 5531Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciBSP416344:GL9Z-2355-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, Monomeric isocitrate dehydrogenaseImported
    Gene namesi
    ORF Names:MYA_2288Imported
    OrganismiBurkholderia sp. KJ006Imported
    Taxonomic identifieri416344 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
    ProteomesiUP000010108: Chromosome 1

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni133 – 1408Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    I2DPS2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTSPKIIYT LTDEAPALAT YSLLPIVKAF THSSGVAVET RDISLAGRII    50
    AAFADVLPPE QKGSDDLADL GQLTLKPEAN IIKLPNISAS VPQLKAAIAE 100
    LQAQGYKLPA YPEEPSTDEE KAVKARYDKI KGSAVNPVLR EGNSDRRAPL 150
    SVKNYARKHP HKMGAWKPTS KSHVAHMTDG DFYGSEKSAL IADAGSVKIE 200
    LTTTDGVKKV LKEKTAVKAG EVIDASVMSR KALRSFIEAQ IADAKAQDVL 250
    FSVHLKATMM KVSDPIMFGH FVSVFYGDVL AKHADVLAQA GFNPNNGIGD 300
    LYARLKDLPA DTREAIEADI KAEYAVRPRL AMVNSDKGIT NLHVPSDVIV 350
    DASMPAMIRD SGGMWGVDGQ LHDAKAVIPD RCYAGVYQAV IEDCKQHGAF 400
    DPVTMGSVPN VGLMAQAAEE YGSHDKTFLI PADGVVRVTD EAGNVLLEHA 450
    VESGDIWRMC QTKDAPVQDW VKLAVNRARA TGAPAVFWLD PVRAHDAQII 500
    AKVERYLKDH DTNGLDIRIM TPVDATRFSL ERIRAGKDTI SVTGNVLRDY 550
    LTDLFPIMEL GTSAKMLSIV PLMAGGGMFE TGAGGSAPKH VQQFVEEGFL 600
    RWDSLGEFLA LAASLEHLGN AYHNPKALVL AKTLDRATGK FLDENRSPAR 650
    KVGGIDNRGS HFYLCMYWAQ ALAEQTEDAA LKAQFEGVAK SLADNEARIL 700
    EELGAAQGKA QAIGGYYRPD VALTSQAMRP SATLNAIVDA VA 742
    Length:742
    Mass (Da):80,022
    Last modified:July 11, 2012 - v1
    Checksum:i3454ED5518C66C8C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003514 Genomic DNA. Translation: AFJ86648.1.
    RefSeqiWP_014723497.1. NC_017920.1.
    YP_006333379.1. NC_017920.1.

    Genome annotation databases

    EnsemblBacteriaiAFJ86648; AFJ86648; MYA_2288.
    GeneIDi12968695.
    KEGGibuk:MYA_2288.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003514 Genomic DNA. Translation: AFJ86648.1 .
    RefSeqi WP_014723497.1. NC_017920.1.
    YP_006333379.1. NC_017920.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFJ86648 ; AFJ86648 ; MYA_2288 .
    GeneIDi 12968695.
    KEGGi buk:MYA_2288.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci BSP416344:GL9Z-2355-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of the Endophytic Bacterium Burkholderia sp. Strain KJ006."
      Kwak M.J., Song J.Y., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K., Lee C.H., Yu D.S., Park S.H., Kim J.F.
      J. Bacteriol. 194:4432-4433(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KJ006Imported.

    Entry informationi

    Entry nameiI2DPS2_9BURK
    AccessioniPrimary (citable) accession number: I2DPS2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 11, 2012
    Last sequence update: July 11, 2012
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3