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I2DPS2

- I2DPS2_9BURK

UniProt

I2DPS2 - I2DPS2_9BURK

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Protein
Submitted name:

Isocitrate dehydrogenase, Monomeric isocitrate dehydrogenase

Gene

MYA_2288

Organism
Burkholderia sp. KJ006
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461SubstrateUniRule annotation
Sitei256 – 2561Critical for catalysisUniRule annotation
Sitei421 – 4211Critical for catalysisUniRule annotation
Binding sitei548 – 5481SubstrateUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBSP416344:GL9Z-2355-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, Monomeric isocitrate dehydrogenaseImported
Gene namesi
ORF Names:MYA_2288Imported
OrganismiBurkholderia sp. KJ006Imported
Taxonomic identifieri416344 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000010108: Chromosome 1

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate bindingUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

I2DPS2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTSPKIIYT LTDEAPALAT YSLLPIVKAF THSSGVAVET RDISLAGRII
60 70 80 90 100
AAFADVLPPE QKGSDDLADL GQLTLKPEAN IIKLPNISAS VPQLKAAIAE
110 120 130 140 150
LQAQGYKLPA YPEEPSTDEE KAVKARYDKI KGSAVNPVLR EGNSDRRAPL
160 170 180 190 200
SVKNYARKHP HKMGAWKPTS KSHVAHMTDG DFYGSEKSAL IADAGSVKIE
210 220 230 240 250
LTTTDGVKKV LKEKTAVKAG EVIDASVMSR KALRSFIEAQ IADAKAQDVL
260 270 280 290 300
FSVHLKATMM KVSDPIMFGH FVSVFYGDVL AKHADVLAQA GFNPNNGIGD
310 320 330 340 350
LYARLKDLPA DTREAIEADI KAEYAVRPRL AMVNSDKGIT NLHVPSDVIV
360 370 380 390 400
DASMPAMIRD SGGMWGVDGQ LHDAKAVIPD RCYAGVYQAV IEDCKQHGAF
410 420 430 440 450
DPVTMGSVPN VGLMAQAAEE YGSHDKTFLI PADGVVRVTD EAGNVLLEHA
460 470 480 490 500
VESGDIWRMC QTKDAPVQDW VKLAVNRARA TGAPAVFWLD PVRAHDAQII
510 520 530 540 550
AKVERYLKDH DTNGLDIRIM TPVDATRFSL ERIRAGKDTI SVTGNVLRDY
560 570 580 590 600
LTDLFPIMEL GTSAKMLSIV PLMAGGGMFE TGAGGSAPKH VQQFVEEGFL
610 620 630 640 650
RWDSLGEFLA LAASLEHLGN AYHNPKALVL AKTLDRATGK FLDENRSPAR
660 670 680 690 700
KVGGIDNRGS HFYLCMYWAQ ALAEQTEDAA LKAQFEGVAK SLADNEARIL
710 720 730 740
EELGAAQGKA QAIGGYYRPD VALTSQAMRP SATLNAIVDA VA
Length:742
Mass (Da):80,022
Last modified:July 11, 2012 - v1
Checksum:i3454ED5518C66C8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003514 Genomic DNA. Translation: AFJ86648.1.
RefSeqiWP_014723497.1. NC_017920.1.
YP_006333379.1. NC_017920.1.

Genome annotation databases

EnsemblBacteriaiAFJ86648; AFJ86648; MYA_2288.
GeneIDi12968695.
KEGGibuk:MYA_2288.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003514 Genomic DNA. Translation: AFJ86648.1 .
RefSeqi WP_014723497.1. NC_017920.1.
YP_006333379.1. NC_017920.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFJ86648 ; AFJ86648 ; MYA_2288 .
GeneIDi 12968695.
KEGGi buk:MYA_2288.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci BSP416344:GL9Z-2355-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of the Endophytic Bacterium Burkholderia sp. Strain KJ006."
    Kwak M.J., Song J.Y., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K., Lee C.H., Yu D.S., Park S.H., Kim J.F.
    J. Bacteriol. 194:4432-4433(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KJ006Imported.

Entry informationi

Entry nameiI2DPS2_9BURK
AccessioniPrimary (citable) accession number: I2DPS2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: November 26, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3