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I2DPS2

- I2DPS2_9BURK

UniProt

I2DPS2 - I2DPS2_9BURK

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Protein
Submitted name: Isocitrate dehydrogenase, Monomeric isocitrate dehydrogenase
Gene
MYA_2288
Organism
Burkholderia sp. KJ006
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei146 – 1461Substrate By similarity
Sitei256 – 2561Critical for catalysis By similarityUniRule annotation
Metal bindingi351 – 3511Magnesium or manganese By similarityUniRule annotation
Sitei421 – 4211Critical for catalysis By similarityUniRule annotation
Binding sitei548 – 5481Substrate By similarityUniRule annotation
Metal bindingi549 – 5491Magnesium or manganese By similarityUniRule annotation
Metal bindingi553 – 5531Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBSP416344:GL9Z-2355-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, Monomeric isocitrate dehydrogenaseImported
Gene namesi
ORF Names:MYA_2288Imported
OrganismiBurkholderia sp. KJ006Imported
Taxonomic identifieri416344 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000010108: Chromosome 1

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni133 – 1408Substrate binding By similarity

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

I2DPS2-1 [UniParc]FASTAAdd to Basket

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MSTSPKIIYT LTDEAPALAT YSLLPIVKAF THSSGVAVET RDISLAGRII    50
AAFADVLPPE QKGSDDLADL GQLTLKPEAN IIKLPNISAS VPQLKAAIAE 100
LQAQGYKLPA YPEEPSTDEE KAVKARYDKI KGSAVNPVLR EGNSDRRAPL 150
SVKNYARKHP HKMGAWKPTS KSHVAHMTDG DFYGSEKSAL IADAGSVKIE 200
LTTTDGVKKV LKEKTAVKAG EVIDASVMSR KALRSFIEAQ IADAKAQDVL 250
FSVHLKATMM KVSDPIMFGH FVSVFYGDVL AKHADVLAQA GFNPNNGIGD 300
LYARLKDLPA DTREAIEADI KAEYAVRPRL AMVNSDKGIT NLHVPSDVIV 350
DASMPAMIRD SGGMWGVDGQ LHDAKAVIPD RCYAGVYQAV IEDCKQHGAF 400
DPVTMGSVPN VGLMAQAAEE YGSHDKTFLI PADGVVRVTD EAGNVLLEHA 450
VESGDIWRMC QTKDAPVQDW VKLAVNRARA TGAPAVFWLD PVRAHDAQII 500
AKVERYLKDH DTNGLDIRIM TPVDATRFSL ERIRAGKDTI SVTGNVLRDY 550
LTDLFPIMEL GTSAKMLSIV PLMAGGGMFE TGAGGSAPKH VQQFVEEGFL 600
RWDSLGEFLA LAASLEHLGN AYHNPKALVL AKTLDRATGK FLDENRSPAR 650
KVGGIDNRGS HFYLCMYWAQ ALAEQTEDAA LKAQFEGVAK SLADNEARIL 700
EELGAAQGKA QAIGGYYRPD VALTSQAMRP SATLNAIVDA VA 742
Length:742
Mass (Da):80,022
Last modified:July 11, 2012 - v1
Checksum:i3454ED5518C66C8C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003514 Genomic DNA. Translation: AFJ86648.1.
RefSeqiWP_014723497.1. NC_017920.1.
YP_006333379.1. NC_017920.1.

Genome annotation databases

EnsemblBacteriaiAFJ86648; AFJ86648; MYA_2288.
GeneIDi12968695.
KEGGibuk:MYA_2288.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003514 Genomic DNA. Translation: AFJ86648.1 .
RefSeqi WP_014723497.1. NC_017920.1.
YP_006333379.1. NC_017920.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFJ86648 ; AFJ86648 ; MYA_2288 .
GeneIDi 12968695.
KEGGi buk:MYA_2288.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci BSP416344:GL9Z-2355-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of the Endophytic Bacterium Burkholderia sp. Strain KJ006."
    Kwak M.J., Song J.Y., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K., Lee C.H., Yu D.S., Park S.H., Kim J.F.
    J. Bacteriol. 194:4432-4433(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KJ006Imported.

Entry informationi

Entry nameiI2DPS2_9BURK
AccessioniPrimary (citable) accession number: I2DPS2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 3, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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