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Protein
Submitted name:

Translation elongation factor Tu

Gene

tuf

Organism
Burkholderia sp. KJ006
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSP416344:GL9Z-268-MONOMER.
BSP416344:GL9Z-282-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Translation elongation factor TuImported
Gene namesi
Name:tufUniRule annotation
ORF Names:MYA_0254Imported, MYA_0267Imported
OrganismiBurkholderia sp. KJ006Imported
Taxonomic identifieri416344 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000010108 Componenti: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiI2DIZ7.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliI2DIZ7.
SMRiI2DIZ7. Positions 2-395.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I2DIZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEKFERTK PHVNVGTIGH VDHGKTTLTA AITTVLTKKF GGEAKAYDQI
60 70 80 90 100
DAAPEEKARG ITINTAHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFLNKCDM VDDAELLELV
160 170 180 190 200
EMEVRELLSK YDFPGDDTPI VKGSAKLALE GDTGELGEVA IMNLADALDT
210 220 230 240 250
YIPTPERAVD GAFLMPVEDV FSISGRGTVV TGRVERGIVK VGEEIEIVGI
260 270 280 290 300
KPTVKTTCTG VEMFRKLLDQ GQAGDNVGIL LRGTKREDVE RGQVLAKPGS
310 320 330 340 350
ITPHTHFTAE VYVLSKDEGG RHTPFFNNYR PQFYFRTTDV TGSIELPKDK
360 370 380 390
EMVMPGDNVS ITVKLIAPIA MEEGLRFAIR EGGRTVGAGV VAKIIE
Length:396
Mass (Da):43,033
Last modified:July 10, 2012 - v1
Checksum:iFF0C340F74D51337
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003514 Genomic DNA. Translation: AFJ84623.1.
CP003514 Genomic DNA. Translation: AFJ84636.1.
RefSeqiYP_006331354.1. NC_017920.1.
YP_006331367.1. NC_017920.1.

Genome annotation databases

EnsemblBacteriaiAFJ84623; AFJ84623; MYA_0254.
AFJ84636; AFJ84636; MYA_0267.
KEGGibuk:MYA_0254.
buk:MYA_0267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003514 Genomic DNA. Translation: AFJ84623.1.
CP003514 Genomic DNA. Translation: AFJ84636.1.
RefSeqiYP_006331354.1. NC_017920.1.
YP_006331367.1. NC_017920.1.

3D structure databases

ProteinModelPortaliI2DIZ7.
SMRiI2DIZ7. Positions 2-395.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiI2DIZ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFJ84623; AFJ84623; MYA_0254.
AFJ84636; AFJ84636; MYA_0267.
KEGGibuk:MYA_0254.
buk:MYA_0267.

Phylogenomic databases

KOiK02358.

Enzyme and pathway databases

BioCyciBSP416344:GL9Z-268-MONOMER.
BSP416344:GL9Z-282-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete Genome Sequence of the Endophytic Bacterium Burkholderia sp. Strain KJ006."
    Kwak M.J., Song J.Y., Kim S.Y., Jeong H., Kang S.G., Kim B.K., Kwon S.K., Lee C.H., Yu D.S., Park S.H., Kim J.F.
    J. Bacteriol. 194:4432-4433(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KJ006Imported.
  2. Kwak M.-J., Song J.Y., Kim S.-Y., Jeong H., Kim B.K., Kwon S.-K., Lee C.H., Yu D.S., Park S.-H., Kim J.F.
    Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: KJ006Imported.

Entry informationi

Entry nameiI2DIZ7_9BURK
AccessioniPrimary (citable) accession number: I2DIZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2012
Last sequence update: July 10, 2012
Last modified: March 31, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.