I2DGK7 (I2DGK7_HELPX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

ORF Names:

MWE_1098 EMBL AFJ81873.1

Organism

Helicobacter pylori XZ274 EMBL AFJ81873.1

Taxonomic identifier

1127122 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	379 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I2DGK7 [UniParc]. Last modified July 11, 2012. Version 1. Checksum: BF90501E0D8ED3CC	FASTA	379	42,072
	10 20 30 40 50 60 MGMLKRASFV EVNSASLRHN FSTVKSIVSK DAHIMAVVKA NAYGAGAIKA SEIFLQEGAH 70 80 90 100 110 120 YLGVATLDEA LELRSHFSKT PILILGYSPN SNASMLIDND LSTMIFSLEQ AEVFSQMALK 130 140 150 160 170 180 SQKRLKVHLK IDTGMHRLGL EPNFKSIETI KKIRALKGLE VEGIFTHLSN ADAKIKTHAK 190 200 210 220 230 240 NQMKAFNAFL EQLLNQKIEF QYRHAYNSAG ILSLCNGNEN RFLNLYRPGI MLYGFYPSNG 250 260 270 280 290 300 MKETCPTILK NVISLKAQIV QIRSVKKGEF IGYGEHFYTN EETLVGVLAL GYADGLMRAL 310 320 330 340 350 360 GNRIQVAINN QLAPLIGKVC MDQCFVKLNN IQAKEGDEVI LFGDKSAKAN DASEIAALLN 370 TIPYETISTL SKRLERVYI

References

[1]

"Genome of Helicobacter pylori Strain XZ274, an Isolate from a Tibetan Patient with Gastric Cancer in China." Guo Y., Wang H., Li Y., Song Y., Chen C., Liao Y., Ren L., Guo C., Tong W., Shen W., Chen M., Mao X., Guo G., Zuo Q. J. Bacteriol. 194:4146-4147(2012) Cited for: NUCLEOTIDE SEQUENCE. Strain: XZ274 EMBL AFJ81873.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003419 Genomic DNA. Translation: AFJ81873.1.
RefSeq	YP_006338564.1. NC_017926.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFJ81873; AFJ81873; MWE_1098.
GeneID	12973925.
KEGG	hey:MWE_1098.
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I2DGK7_HELPX

Accession

Primary (citable) accession number: I2DGK7

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2012
Last sequence update:	July 11, 2012
Last modified:	April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)