Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

I2DGK7 (I2DGK7_HELPX) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2731Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1371Substrate By similarity HAMAP-Rule MF_01201
Binding site3211Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
I2DGK7 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: BF90501E0D8ED3CC

FASTA37942,072
        10         20         30         40         50         60 
MGMLKRASFV EVNSASLRHN FSTVKSIVSK DAHIMAVVKA NAYGAGAIKA SEIFLQEGAH 

        70         80         90        100        110        120 
YLGVATLDEA LELRSHFSKT PILILGYSPN SNASMLIDND LSTMIFSLEQ AEVFSQMALK 

       130        140        150        160        170        180 
SQKRLKVHLK IDTGMHRLGL EPNFKSIETI KKIRALKGLE VEGIFTHLSN ADAKIKTHAK 

       190        200        210        220        230        240 
NQMKAFNAFL EQLLNQKIEF QYRHAYNSAG ILSLCNGNEN RFLNLYRPGI MLYGFYPSNG 

       250        260        270        280        290        300 
MKETCPTILK NVISLKAQIV QIRSVKKGEF IGYGEHFYTN EETLVGVLAL GYADGLMRAL 

       310        320        330        340        350        360 
GNRIQVAINN QLAPLIGKVC MDQCFVKLNN IQAKEGDEVI LFGDKSAKAN DASEIAALLN 

       370 
TIPYETISTL SKRLERVYI 

« Hide

References

[1]"Genome of Helicobacter pylori strain XZ274, an isolate from a tibetan patient with gastric cancer in China."
Guo Y., Wang H., Li Y., Song Y., Chen C., Liao Y., Ren L., Guo C., Tong W., Shen W., Chen M., Mao X., Guo G., Zou Q.
J. Bacteriol. 194:4146-4147(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: XZ274 EMBL AFJ81873.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003419 Genomic DNA. Translation: AFJ81873.1.
RefSeqYP_006338564.1. NC_017926.1.

3D structure databases

ProteinModelPortalI2DGK7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFJ81873; AFJ81873; MWE_1098.
GeneID12973925.
KEGGhey:MWE_1098.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycHPYL1127122:GLEU-1007-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI2DGK7_HELPX
AccessionPrimary (citable) accession number: I2DGK7
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: April 16, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)