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I2C1K9 (I2C1K9_BACAM) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL AFJ60533.1
ORF Names:MUS_0459 EMBL AFJ60533.1
OrganismBacillus amyloliquefaciens Y2 EMBL AFJ60533.1
Taxonomic identifier1126211 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity SAAS SAAS005905 HAMAP-Rule MF_00047.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. SAAS SAAS005905 HAMAP-Rule MF_00047

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain133 – 338206ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding166 – 22156ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2921Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3051Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3051Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3071Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
I2C1K9 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: DB7EA78B5E44C06A

FASTA35439,217
        10         20         30         40         50         60 
MYGGKSAEHN VSLQTALAVT KALNTEKFDI HPIYITEKGE WQRGPLLTEP VSNVKMLQLE 

        70         80         90        100        110        120 
QNGESFALSA LNREMFPEAS PDEKAPIDVV FPLLHGPNGE DGTIQGLLEL LNVPYVGNGV 

       130        140        150        160        170        180 
LASSAGMDKV IMKHLFAQAG LPQAKYAAFL KKDWKQTPDS CLQQVEEELG YPCFVKPANL 

       190        200        210        220        230        240 
GSSVGISKCR NREELEKAFE LAFEYDRKIV VEEGIAGREI EIGVLGNDEP KCSAVGEIAP 

       250        260        270        280        290        300 
KTDFYDYKAK YEDGDTDLMI PAQVTDEQYA EISEMAIKAF KAIDGSGLVR ADFFLTNDGQ 

       310        320        330        340        350 
VLINEVNTMP GFTPFSMFPL LWKEAGVDYS DLIEQLVELA KERHAEKQLI KHTF

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References

[1]"Elucidating bio-control and plant multi-beneficial properties of Bacillus amyloliquefaciens Y2 with its Genome."
Hao K., He P., Wu Y., Wang Z., Wu X., Yu X., Cheng Q., Yin J., Borriss R., Mao Z., He Y.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Y2 EMBL AFJ60533.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003332 Genomic DNA. Translation: AFJ60533.1.
RefSeqYP_006327258.1. NC_017912.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFJ60533; AFJ60533; MUS_0459.
GeneID12963592.
KEGGbqy:MUS_0459.

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI2C1K9_BACAM
AccessionPrimary (citable) accession number: I2C1K9
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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