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Protein

Guanylate kinase

Gene

gmk

Organism
Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74) (Escherichia blattae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi31 – 38ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:EBL_c39230Imported
OrganismiShimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74) (Escherichia blattae)Imported
Taxonomic identifieri630626 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShimwellia
Proteomesi
  • UP000001955 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 204Guanylate kinase-likeInterPro annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

I2BEJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIISGYTHS FFVYQLNKTH MAQGTLYIVS APSGAGKSSL IQALLKTQPL
60 70 80 90 100
YDTQVSVSHT TRAARPGEVH GEHYFFVSKD EFREMITRDA FLEHAEVFGN
110 120 130 140 150
YYGTSRETIE QVLATGVDVF LDIDWQGAQQ IRTKMPHARS IFILPPSKIE
160 170 180 190 200
LDRRLRGRGQ DSEEVIARRM AQAVAEMSHY AEYDYLIVND DFDTALADLK
210 220
IIIRAERLRM SRQKQRHDAL ISKLLAD
Length:227
Mass (Da):25,900
Last modified:July 11, 2012 - v1
Checksum:iC2386FC0CC9FE2DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001560 Genomic DNA. Translation: AFJ48951.1.

Genome annotation databases

EnsemblBacteriaiAFJ48951; AFJ48951; EBL_c39230.
KEGGiebt:EBL_c39230.
PATRICifig|630626.3.peg.3821.

Similar proteinsi

Entry informationi

Entry nameiI2BEJ7_SHIBC
AccessioniPrimary (citable) accession number: I2BEJ7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 27, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported