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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74) (Escherichia blattae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei546 – 5461UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciEBLA630626:GLCZ-3850-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:EBL_c38500Imported
OrganismiShimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74) (Escherichia blattae)Imported
Taxonomic identifieri630626 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShimwellia
ProteomesiUP000001955 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I2BEC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNERYSALRS NVSMLGKLLG DTIRDALGEN ILDRVETIRK LSKSSRAGNE
60 70 80 90 100
SDRQALLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS MSPHGEAANN
110 120 130 140 150
PEIIANTVRK LREEHALSDA DIRHSLESLS LELVLTAHPT EITRRTLIHK
160 170 180 190 200
LVEVNSCLKQ LDHNDLTDYE RNLVMRRLRQ LIAQSWHTDE IRKHRPTPVD
210 220 230 240 250
EAKWGFAVVE NSLWEGVPNY LRELNEQLDE TLDYKLPVDF VPVRFTSWMG
260 270 280 290 300
GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDIQVLISEL SMVECTDELR
310 320 330 340 350
QRVGDEGEQE PYRYLMKQLR SQLMSTQAWL EARLKGQKLP KPKDLITHNA
360 370 380 390 400
QLWDPLLACY NSLQACGMGI IANGELLDTL RRVKAFGVPL VRIDIRQEST
410 420 430 440 450
RHSEALGEIT RYLGLGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSAD
460 470 480 490 500
TREVLDTCKV IAEAPQGSIA AYVISMAKTP SDVLAVHLLL KEAGISFAMP
510 520 530 540 550
VAPLFETLED LNNANDVMSQ LLSIDWYRGF IQGKQMVMIG YSDSAKDAGV
560 570 580 590 600
MAASWAQYQA QDALIKTCEK AGIALTLFHG RGGSIGRGGA PAHAALLSQP
610 620 630 640 650
PGSLKGGLRV TEQGEMIRFK YGLPEVTVAS LSLYTSAILE ANLLPPPEPK
660 670 680 690 700
PEWRRIMDEL STISCDMYRG YIRENKDFVP YFRSATPELE LGKLPLGSRP
710 720 730 740 750
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEDGRQSKL
760 770 780 790 800
EAMCRDWPFF STRLGMLEMV FAKADLWLAE YYDQRLVNTA LWPLGLELRK
810 820 830 840 850
QLEADIKLVL AIANDAHLMA DLPWIAESIT LRNIYTDPLN VLQAELLHRS
860 870 880
RQAEEQGAQP DPRVEQALMV TIAGVAAGMR NTG
Length:883
Mass (Da):99,236
Last modified:July 11, 2012 - v1
Checksum:i565EE29F81CB62F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001560 Genomic DNA. Translation: AFJ48878.1.
RefSeqiWP_002442697.1. NZ_BAHA01000017.1.
YP_006321389.1. NC_017910.1.

Genome annotation databases

EnsemblBacteriaiAFJ48878; AFJ48878; EBL_c38500.
GAB81849; GAB81849; EB105725_17_00980.
KEGGiebt:EBL_c38500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001560 Genomic DNA. Translation: AFJ48878.1.
RefSeqiWP_002442697.1. NZ_BAHA01000017.1.
YP_006321389.1. NC_017910.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFJ48878; AFJ48878; EBL_c38500.
GAB81849; GAB81849; EB105725_17_00980.
KEGGiebt:EBL_c38500.

Phylogenomic databases

KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciEBLA630626:GLCZ-3850-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of the B12 producing Escherichia blattae strain DSM4481 isolated from a cockroach."
    Daniel R.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74Imported.

Entry informationi

Entry nameiI2BEC4_SHIBC
AccessioniPrimary (citable) accession number: I2BEC4
Secondary accession number(s): K6VYR2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: June 24, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.