Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamate decarboxylase

Gene

W7S_21285

Organism
Mycobacterium sp. MOTT36Y
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciMSP1168287:GLGR-4263-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:W7S_21285Imported
OrganismiMycobacterium sp. MOTT36YImported
Taxonomic identifieri1168287 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
ProteomesiUP000002868 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

I2AIT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQHPSLPAH SIAPAYTGRL FTAPVPALRM PDESMDPDAA YRFIHDELML
60 70 80 90 100
DGSSRLNLAT FVTTWMDPEA GKLMAETFDK NMIDKDEYPA TAAIEQRCVC
110 120 130 140 150
MVADLFHADG LNDADPYSAC GVSTIGSSEA VMLGGLAMKW RWRAKIGKDW
160 170 180 190 200
KDRTPNLVMG SNVQVVWEKF CRYFDVEPRY LPMEEGRYVI TPEQVVDAVD
210 220 230 240 250
ENTIGVVAIL GTTYTGELEP VADICGALDK LAAGGGVDVP VHVDAASGGF
260 270 280 290 300
VVPFLHPELK WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RSKEYLPDDL
310 320 330 340 350
VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGREGY TKVMQALSGT
360 370 380 390 400
ARWLGEQLRV SEHCELVSDG SAIPVVAFRL SKDRGYTEFD VSHELRTYGW
410 420 430 440 450
QVPAYTMPDN ATNVSVLRIV VREGLSADLA RALHDDAVSA LSSLDKLRPG
460
GHYADQHFAH
Length:460
Mass (Da):50,906
Last modified:July 11, 2012 - v1
Checksum:iE6A2736341D4D6A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003491 Genomic DNA. Translation: AFJ37206.1.
RefSeqiWP_014712324.1. NC_017904.1.

Genome annotation databases

EnsemblBacteriaiAFJ37206; AFJ37206; W7S_21285.
KEGGimmm:W7S_21285.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003491 Genomic DNA. Translation: AFJ37206.1.
RefSeqiWP_014712324.1. NC_017904.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFJ37206; AFJ37206; W7S_21285.
KEGGimmm:W7S_21285.

Phylogenomic databases

KOiK01580.

Enzyme and pathway databases

BioCyciMSP1168287:GLGR-4263-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-36Y, belonging to the INT5 genotype."
    Kim B.J., Choi B.S., Choi I.Y., Lee J.H., Chun J., Hong S.H., Kook Y.H., Kim B.J.
    J. Bacteriol. 194:4141-4142(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MOTT36YImported.

Entry informationi

Entry nameiI2AIT2_9MYCO
AccessioniPrimary (citable) accession number: I2AIT2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: July 22, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.