I2AIT1 (I2AIT1_9MYCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr EMBL AFJ37205.1
ORF Names:	W7S_21280 EMBL AFJ37205.1

Organism

Mycobacterium sp. MOTT36Y EMBL AFJ37205.1

Taxonomic identifier

1168287 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL AFJ37205.1
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	I2AIT1 [UniParc]. Last modified July 11, 2012. Version 1. Checksum: 84AF306C9AB1199C	FASTA	391	41,404
	10 20 30 40 50 60 MTGRAATPIS LTPGLLAEAL VDLGAIAHNV RLLCEQAGGA QVMAVVKADG YGHGAAQTAR 70 80 90 100 110 120 AALAAGAAEL GVATVDEALA LRADGVRAPV LAWLHPPGFD FAPALLADIQ IAVSSERQLD 130 140 150 160 170 180 ELLDAVRRTG RTATVTVKVD TGLNRNGVPP EHYPSMLTAL RRAVAENAIV LRGLMSHMVY 190 200 210 220 230 240 ADQPANPVND LQAQRFTEML AQARDQGVRY EAAHLSNSSA TMSRPDLAFD MVRPGIAVYG 250 260 270 280 290 300 LSPVPELGDM GLIPAMTVKC PVALVKSIRA GESVSYGHTW TARRDTTLAL LPVGYADGVF 310 320 330 340 350 360 RSLGNRLEVL INGRRRPGVG RICMDQFVVD LGPGPTDVAE GDEAILFGPG ASGEPTAQDW 370 380 390 ADLLGTIHYE VVTSPRGRIT RTYREARTIE P

References

[1]

"Complete Genome Sequence of Mycobacterium intracellulare Clinical Strain MOTT-36Y, Belonging to the INT5 Genotype." Kim B.-J., Choi B.-S., Choi I.-Y., Lee J.-H., Chun J., Hong S.-H., Kook Y.-H., Kim B.-J. J. Bacteriol. 194:4141-4142(2012) Cited for: NUCLEOTIDE SEQUENCE. Strain: MOTT36Y EMBL AFJ37205.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP003491 Genomic DNA. Translation: AFJ37205.1.
RefSeq	YP_006307932.1. NC_017904.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AFJ37205; AFJ37205; W7S_21280.
GeneID	12939497.
KEGG	mmm:W7S_21280.
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

I2AIT1_9MYCO

Accession

Primary (citable) accession number: I2AIT1

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2012
Last sequence update:	July 11, 2012
Last modified:	April 3, 2013
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)