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I2AFT5

- I2AFT5_9MYCO

UniProt

I2AFT5 - I2AFT5_9MYCO

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, W7S_15990
Organism
Mycobacterium sp. MOTT36Y
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarityUniRule annotation
Active sitei596 – 5961 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciMSP1168287:GLGR-3208-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:W7S_15990Imported
OrganismiMycobacterium sp. MOTT36YImported
Taxonomic identifieri1168287 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000002868: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I2AFT5-1 [UniParc]FASTAAdd to Basket

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MADASEAPED TLEPIGAVQR TPVGRAATEP MRADIRLLGA ILGDTVREQN    50
GREVFELVER ARVESFRVRR SEIDRAELAR MFYRIDIHQA IPVIRAFSHF 100
ALLANVAEDI HRERRRAVHV AAGEPPPDST LAATYAKLDE AQLDSDTVAD 150
ALKGAVVAPV ITAHPTETRR RTVFVTQHRI NELMRLHAEG HAETDDGRNI 200
ELELRRQVLT LWQTALIRLS RLQITDEIEV GLRYYAAAFF KVIPQVNAEV 250
RDTLRARWPD ADLFDEPMLQ PGSWIGGDRD GNPNVTADVV RQATGSAAFT 300
ALAHYLAELT ALEQELSMSA RLVSVTPALT ELAGGCAEKA RADEPYRRAV 350
RVIRARLSAT SAAILDRTPQ QVLDLGLPPY ETPAELGADL DTMDESLRGH 400
GSALLADDRL ALLREGVRVF GFHLCGLDMR QNSDAHEEVI CELLAWAGVH 450
PDYRSLPEDE RVELLAAELG TRRPLVADDA QLSDLARGEL DVVRAAAHAI 500
KRYGPSAVPN YVISMCRSVS DVLEAAILLK EAGLIDASGP EPYCPVGISP 550
LFETIDDLHN GATILHAMLE LPIYRALVAA RGETQEVMLG YSDSNKDGGY 600
LASSWAVYRA ELALVEVARK TGIRLRLFHG RGGTVGRGGG PSYEAILAQP 650
PGAVNGSLRL TEQGEVIAAK YAEPRVAQRN LESLLAATLE STLLDVEGLG 700
DAAEPAYAVL DEVAVLAQRA YAELVHDTPG FVDYFMASTP VSEIGSLNIG 750
SRPTSRKPTE SISDLRAIPW VLAWSQSRVM LPGWYGTGSA FEQWIAAGPQ 800
SEAERVSILH DLYQRWPFFR SVLSNLAQVL AKSDLGLAAR YAELVDDEEL 850
RRRVFGKIVD EHGRTIAMHK LITGQDNLLA DNPALARSVF NRFPYLEPLN 900
HLQVELLRRY RSGDDDELVQ RGILLTMNGL ASALRNSG 938
Length:938
Mass (Da):102,939
Last modified:July 11, 2012 - v1
Checksum:i4D31A43F0F08C903
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003491 Genomic DNA. Translation: AFJ36159.1.
RefSeqiYP_006306886.1. NC_017904.1.

Genome annotation databases

EnsemblBacteriaiAFJ36159; AFJ36159; W7S_15990.
GeneIDi12942319.
KEGGimmm:W7S_15990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003491 Genomic DNA. Translation: AFJ36159.1 .
RefSeqi YP_006306886.1. NC_017904.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFJ36159 ; AFJ36159 ; W7S_15990 .
GeneIDi 12942319.
KEGGi mmm:W7S_15990.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci MSP1168287:GLGR-3208-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-36Y, belonging to the INT5 genotype."
    Kim B.J., Choi B.S., Choi I.Y., Lee J.H., Chun J., Hong S.H., Kook Y.H., Kim B.J.
    J. Bacteriol. 194:4141-4142(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MOTT36YImported.

Entry informationi

Entry nameiI2AFT5_9MYCO
AccessioniPrimary (citable) accession number: I2AFT5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: September 3, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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