Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

I2AFT5 (I2AFT5_9MYCO) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
ORF Names:W7S_15990 EMBL AFJ36159.1
OrganismMycobacterium sp. MOTT36Y [Complete proteome] EMBL AFJ36159.1
Taxonomic identifier1168287 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length938 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS021135

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1641 By similarity HAMAP-Rule MF_00595
Active site5961 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
I2AFT5 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: 4D31A43F0F08C903

FASTA938102,939
        10         20         30         40         50         60 
MADASEAPED TLEPIGAVQR TPVGRAATEP MRADIRLLGA ILGDTVREQN GREVFELVER 

        70         80         90        100        110        120 
ARVESFRVRR SEIDRAELAR MFYRIDIHQA IPVIRAFSHF ALLANVAEDI HRERRRAVHV 

       130        140        150        160        170        180 
AAGEPPPDST LAATYAKLDE AQLDSDTVAD ALKGAVVAPV ITAHPTETRR RTVFVTQHRI 

       190        200        210        220        230        240 
NELMRLHAEG HAETDDGRNI ELELRRQVLT LWQTALIRLS RLQITDEIEV GLRYYAAAFF 

       250        260        270        280        290        300 
KVIPQVNAEV RDTLRARWPD ADLFDEPMLQ PGSWIGGDRD GNPNVTADVV RQATGSAAFT 

       310        320        330        340        350        360 
ALAHYLAELT ALEQELSMSA RLVSVTPALT ELAGGCAEKA RADEPYRRAV RVIRARLSAT 

       370        380        390        400        410        420 
SAAILDRTPQ QVLDLGLPPY ETPAELGADL DTMDESLRGH GSALLADDRL ALLREGVRVF 

       430        440        450        460        470        480 
GFHLCGLDMR QNSDAHEEVI CELLAWAGVH PDYRSLPEDE RVELLAAELG TRRPLVADDA 

       490        500        510        520        530        540 
QLSDLARGEL DVVRAAAHAI KRYGPSAVPN YVISMCRSVS DVLEAAILLK EAGLIDASGP 

       550        560        570        580        590        600 
EPYCPVGISP LFETIDDLHN GATILHAMLE LPIYRALVAA RGETQEVMLG YSDSNKDGGY 

       610        620        630        640        650        660 
LASSWAVYRA ELALVEVARK TGIRLRLFHG RGGTVGRGGG PSYEAILAQP PGAVNGSLRL 

       670        680        690        700        710        720 
TEQGEVIAAK YAEPRVAQRN LESLLAATLE STLLDVEGLG DAAEPAYAVL DEVAVLAQRA 

       730        740        750        760        770        780 
YAELVHDTPG FVDYFMASTP VSEIGSLNIG SRPTSRKPTE SISDLRAIPW VLAWSQSRVM 

       790        800        810        820        830        840 
LPGWYGTGSA FEQWIAAGPQ SEAERVSILH DLYQRWPFFR SVLSNLAQVL AKSDLGLAAR 

       850        860        870        880        890        900 
YAELVDDEEL RRRVFGKIVD EHGRTIAMHK LITGQDNLLA DNPALARSVF NRFPYLEPLN 

       910        920        930 
HLQVELLRRY RSGDDDELVQ RGILLTMNGL ASALRNSG 

« Hide

References

[1]"Complete genome sequence of Mycobacterium intracellulare clinical strain MOTT-36Y, belonging to the INT5 genotype."
Kim B.J., Choi B.S., Choi I.Y., Lee J.H., Chun J., Hong S.H., Kook Y.H., Kim B.J.
J. Bacteriol. 194:4141-4142(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MOTT36Y EMBL AFJ36159.1.
[2]Kim B.-J., Choi B.-S., Lim J.-S., Choi I.-Y., Kook Y.-H., Kim B.-J.
Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MOTT36Y EMBL AFJ36159.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003491 Genomic DNA. Translation: AFJ36159.1.
RefSeqYP_006306886.1. NC_017904.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFJ36159; AFJ36159; W7S_15990.
GeneID12942319.
KEGGmmm:W7S_15990.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Enzyme and pathway databases

BioCycMSP1168287:GLGR-3208-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI2AFT5_9MYCO
AccessionPrimary (citable) accession number: I2AFT5
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: April 16, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)