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I2A2V7 (I2A2V7_ECOLX) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339

Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339 EMBL AFJ31631.1
ORF Names:CDCO157_4580 EMBL AFJ31631.1
OrganismEscherichia coli Xuzhou21 [Complete proteome] EMBL AFJ31631.1
Taxonomic identifier741093 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length320 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding22 – 265ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding155 – 1595ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding172 – 18817ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1281Proton acceptor By similarity HAMAP-Rule MF_00339
Metal binding1861Magnesium; via carbonyl oxygen By similarity HAMAP-Rule MF_00339
Metal binding1881Magnesium By similarity HAMAP-Rule MF_00339
Binding site1631Substrate By similarity HAMAP-Rule MF_00339
Binding site2441Substrate By similarity HAMAP-Rule MF_00339
Binding site2501Substrate By similarity HAMAP-Rule MF_00339
Binding site2531Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
I2A2V7 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: D03D79F6A5536A41

FASTA32034,842
        10         20         30         40         50         60 
MIKKIGVLTS GGDAPGMNAA IRGVVRSALT EGLEVMGIYD GYLGLYEDRM VQLDRYSVSD 

        70         80         90        100        110        120 
MINRGGTFLG SARFPEFRDE NIRAVAIENL KKRGIDALVV IGGDGSYMGA MRLTEMGFPC 

       130        140        150        160        170        180 
IGLPGTIDND IKGTDYTIGF FTALSTVVEA IDRLRDTSSS HQRISVVEVM GRYCGDLTLA 

       190        200        210        220        230        240 
AAIAGGCEFV VVPEVEFSRE DLVNEIKAGI AKGKKHAIVA ITEHMCDVDE LAHFIEKETG 

       250        260        270        280        290        300 
RETRATVLGH IQRGGSPVPY DRILASRMGA YAIDLLLAGY GGRCVGIQNE QLVHHDIIDA 

       310        320 
IENMKRPFKG DWLDCAKKLY 

« Hide

References

[1]"A Novel Escherichia coli O157:H7 Clone Causing a Major Hemolytic Uremic Syndrome Outbreak in China."
Xiong Y., Wang P., Lan R., Ye C., Wang H., Ren J., Jing H., Wang Y., Zhou Z., Bai X., Cui Z., Luo X., Zhao A., Wang Y., Zhang S., Sun H., Wang L., Xu J.
PLoS ONE 7:E36144-E36144(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Xuzhou21 EMBL AFJ31631.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001925 Genomic DNA. Translation: AFJ31631.1.
RefSeqYP_006315441.1. NC_017906.1.

3D structure databases

ProteinModelPortalI2A2V7.
SMRI2A2V7. Positions 1-320.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEI2A2V7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFJ31631; AFJ31631; CDCO157_4580.
GeneID12948713.
KEGGelx:CDCO157_4580.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00850.
OMAKMVHHDI.

Enzyme and pathway databases

BioCycECOL741093:GLD7-4678-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012828. PFKA_ATP.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
TIGRFAMsTIGR02482. PFKA_ATP. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI2A2V7_ECOLX
AccessionPrimary (citable) accession number: I2A2V7
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: April 16, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)