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I1XYB6 (I1XYB6_ACIBA) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
ORF Names:ABTJ_01030 EMBL AFI94652.1
OrganismAcinetobacter baumannii MDR-TJ EMBL AFI94652.1
Taxonomic identifier889738 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter › Acinetobacter calcoaceticus/baumannii complex ›

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
I1XYB6 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: B4129B0A73ACB50F

FASTA41845,623
        10         20         30         40         50         60 
MGYQKIVVPA DGDKITVKAD LSLNVPNHPI IPFIEGDGIG VDITPAMKKV VDAAILKAYG 

        70         80         90        100        110        120 
GKRSIEWMEV YCGEKANKIY GTYMPEETFE ALREFVVSIK GPLTTPVGGG IRSLNVALRQ 

       130        140        150        160        170        180 
ELDLYVCVRP VRWFQGVPSP VQHPELTDMV IFRENSEDIY AGIEWKADSE EAKKVIKFLQ 

       190        200        210        220        230        240 
EEMGVTKIRF PEGCGIGIKP VSKEGTQRLV RKAIQFAIDN DKPSVTLVHK GNIMKYTEGA 

       250        260        270        280        290        300 
FKEWGYELAL DRFGGELIDG GPWVKIKNPK NGKDIIIKDV IADAFLQQIL MRPADYSVIA 

       310        320        330        340        350        360 
TLNLNGDYIS DALAAEVGGI GIAPGANIGG AIAVYEATHG TAPKYAGQDK VNPGSIILSA 

       370        380        390        400        410 
EMMLRDMGWT EAADLIIKGI SGAIAAKTVT YDFERLMPGA TLLRCSEFGD AIIQHMED

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References

[1]"Genome sequence of Acinetobacter baumannii MDR-TJ."
Gao F., Wang Y., Liu Y.J., Wu X.M., Lv X., Gan Y.R., Song S.D., Huang H.
J. Bacteriol. 193:2365-2366(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MDR-TJ EMBL AFI94652.1.
[2]"Complete genome sequence of Acinetobacter baumannii MDR-TJ and insights into its mechanism of antibiotic resistance."
Huang H., Yang Z.L., Wu X.M., Wang Y., Liu Y.J., Luo H., Lv X., Gan Y.R., Song S.D., Gao F.
J. Antimicrob. Chemother. 67:2825-2832(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MDR-TJ EMBL AFI94652.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003500 Genomic DNA. Translation: AFI94652.1.
RefSeqYP_006288947.1. NC_017847.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFI94652; AFI94652; ABTJ_01030.
GeneID12840278.
KEGGabr:ABTJ_01030.

Phylogenomic databases

KOK00031.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI1XYB6_ACIBA
AccessionPrimary (citable) accession number: I1XYB6
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: April 3, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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