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I1XYB6

- I1XYB6_ACIBA

UniProt

I1XYB6 - I1XYB6_ACIBA

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Protein

Isocitrate dehydrogenase [NADP]

Gene

ABTJ_01030

Organism
Acinetobacter baumannii MDR-TJ
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciABAU889738:GL7L-1021-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
ORF Names:ABTJ_01030Imported
OrganismiAcinetobacter baumannii MDR-TJImported
Taxonomic identifieri889738 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000009146: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I1XYB6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGYQKIVVPA DGDKITVKAD LSLNVPNHPI IPFIEGDGIG VDITPAMKKV
60 70 80 90 100
VDAAILKAYG GKRSIEWMEV YCGEKANKIY GTYMPEETFE ALREFVVSIK
110 120 130 140 150
GPLTTPVGGG IRSLNVALRQ ELDLYVCVRP VRWFQGVPSP VQHPELTDMV
160 170 180 190 200
IFRENSEDIY AGIEWKADSE EAKKVIKFLQ EEMGVTKIRF PEGCGIGIKP
210 220 230 240 250
VSKEGTQRLV RKAIQFAIDN DKPSVTLVHK GNIMKYTEGA FKEWGYELAL
260 270 280 290 300
DRFGGELIDG GPWVKIKNPK NGKDIIIKDV IADAFLQQIL MRPADYSVIA
310 320 330 340 350
TLNLNGDYIS DALAAEVGGI GIAPGANIGG AIAVYEATHG TAPKYAGQDK
360 370 380 390 400
VNPGSIILSA EMMLRDMGWT EAADLIIKGI SGAIAAKTVT YDFERLMPGA
410
TLLRCSEFGD AIIQHMED
Length:418
Mass (Da):45,623
Last modified:July 11, 2012 - v1
Checksum:iB4129B0A73ACB50F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003500 Genomic DNA. Translation: AFI94652.1.
RefSeqiYP_006288947.1. NC_017847.1.

Genome annotation databases

EnsemblBacteriaiAFI94652; AFI94652; ABTJ_01030.
GeneIDi12840278.
KEGGiabr:ABTJ_01030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003500 Genomic DNA. Translation: AFI94652.1 .
RefSeqi YP_006288947.1. NC_017847.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFI94652 ; AFI94652 ; ABTJ_01030 .
GeneIDi 12840278.
KEGGi abr:ABTJ_01030.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci ABAU889738:GL7L-1021-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MDR-TJImported.

Entry informationi

Entry nameiI1XYB6_ACIBA
AccessioniPrimary (citable) accession number: I1XYB6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: October 29, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3