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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylophaga nitratireducenticrescens (strain ATCC BAA-2433 / DSM 25689 / JAM1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei157 – 1571UniRule annotation
Active sitei604 – 6041UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMSP754476:GLGH-2909-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Q7A_2929Imported
OrganismiMethylophaga nitratireducenticrescens (strain ATCC BAA-2433 / DSM 25689 / JAM1)Imported
Taxonomic identifieri754476 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeMethylophaga
ProteomesiUP000009144 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I1XMT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTRQVDFSS AVALELLTDK DLRSHVRFLV NLLGEVIAEQ SGPEVYQVIE
60 70 80 90 100
QLRKGFIRLR KEDDVELRQT LKDKIESLDE LTLREVIRAF NLYFSLVNTA
110 120 130 140 150
EEAYHHHNRQ IQLRNGGNLW HGSFLDTLTQ FKNEGVLVKQ LQDLLEKLVF
160 170 180 190 200
MPVFTAHPTE SKRRTVMEML RRVFLLDEKL TEGLITPFDQ QQIRNQLKRQ
210 220 230 240 250
IQLLWSTDEV RAVKPSVRDE IKNGLYYFNV SLFDAVPRTY RNFENALRRV
260 270 280 290 300
YGDELDPETP IVVPDYLRFG SWIGGDRDGN PFVTAQTTEM AIALQKRTVI
310 320 330 340 350
RRYLEDVTKL SFILTQSQPL CEINTDLATD IEQSEQRFAG AFSTNPQRFI
360 370 380 390 400
NEPYRRKLYM MRYRLKDNLA VLEEFFRPDL QIESLGVAYH NEDEFLADLY
410 420 430 440 450
LIHKSLVDNG DIAIAAAELT DLIRLVKTFG FYLYNLDIRQ ESSKHTDAVG
460 470 480 490 500
EILALTGLNR HYLQMDEAER QTLLTDLLAA PRLPEIYGDL QPDSLEILNV
510 520 530 540 550
FRLIARLRVE VSEKAFGNYV ISMTHQASHI LEVMLLARFA DLIGQDEHGW
560 570 580 590 600
FCHIRVAPLF ETIEDLEHIE PVMSALLENS QYRTLLSTSG NMQEVMLGYS
610 620 630 640 650
DSCKDGGILA SAWNLYQAQK TVSRLSEQYA IGCRMFHGRG GTIGRGGGPT
660 670 680 690 700
HDAILAQPVD TVHGQIKFTE QGEVLSFKYG NTETAAYELG MGVSALIKAS
710 720 730 740 750
RGLVTDSAQE KPEYLSIMQQ LAQLGEQQYR QLTEQTPGFL DYFYEACPIS
760 770 780 790 800
EIGLMNIGSR PSHRKIADRS KSSVRAIGWV FAWAQSRHTL PGWYGVGSAI
810 820 830 840 850
ATWISDDPER RQILQKMYFE WPFFRAMVSN TQMSLSKADM DIAAEYADLC
860 870 880 890 900
IDKLQAQQVL SVIRTEYQQT ASQLLQLTGA ETLMAENPQL ALSLRRRQAY
910 920 930 940
LDPLNHIQLL LLKRYRHGDY SDAETAKWRD PLLRSISAIS QGMRNTG
Length:947
Mass (Da):108,367
Last modified:July 11, 2012 - v1
Checksum:iF3DAB50A08E4EF0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003390 Genomic DNA. Translation: AFI85706.1.
RefSeqiWP_014708067.1. NC_017857.1.
YP_006297351.1. NC_017857.1.

Genome annotation databases

EnsemblBacteriaiAFI85706; AFI85706; Q7A_2929.
KEGGimej:Q7A_2929.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003390 Genomic DNA. Translation: AFI85706.1.
RefSeqiWP_014708067.1. NC_017857.1.
YP_006297351.1. NC_017857.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFI85706; AFI85706; Q7A_2929.
KEGGimej:Q7A_2929.

Phylogenomic databases

KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciMSP754476:GLGH-2909-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga sp. strain JAM7."
    Villeneuve C., Martineau C., Mauffrey F., Villemur R.
    J. Bacteriol. 194:4126-4127(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JAM1Imported.

Entry informationi

Entry nameiI1XMT7_METNJ
AccessioniPrimary (citable) accession number: I1XMT7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: April 1, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.