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Protein

Superoxide dismutase [Cu-Zn]

Gene

Q7A_2908

Organism
Methylophaga nitratireducenticrescens (strain ATCC BAA-2433 / DSM 25689 / JAM1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMSP754476:GLGH-2888-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Q7A_2908Imported
OrganismiMethylophaga nitratireducenticrescens (strain ATCC BAA-2433 / DSM 25689 / JAM1)Imported
Taxonomic identifieri754476 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeMethylophaga
ProteomesiUP000009144 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 PotentialImportedAdd
BLAST
Chaini19 – 170152 PotentialImportedPRO_5000888381Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

KOiK04565.
OMAiTVEMINA.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

I1XMR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLTCIMIA LTSSVAFADT QIELYEVDKQ GTGKSLGSVA VHQSAFGLVF
60 70 80 90 100
TPDLKSLTPG LHGFHVHQNP SCDAAEKDGE MVPALAAGGH YDPYNTGKHD
110 120 130 140 150
TPWGSGHAGD LPPLYVADDG TATHPVLAPR LTLKDLQGRS LMIHAGGDNH
160 170
SDHPKPLGGG GARVACGVTD
Length:170
Mass (Da):17,686
Last modified:July 11, 2012 - v1
Checksum:iD42153BDFAFF1FD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003390 Genomic DNA. Translation: AFI85685.1.
RefSeqiWP_014708046.1. NC_017857.1.

Genome annotation databases

EnsemblBacteriaiAFI85685; AFI85685; Q7A_2908.
KEGGimej:Q7A_2908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003390 Genomic DNA. Translation: AFI85685.1.
RefSeqiWP_014708046.1. NC_017857.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFI85685; AFI85685; Q7A_2908.
KEGGimej:Q7A_2908.

Phylogenomic databases

KOiK04565.
OMAiTVEMINA.

Enzyme and pathway databases

BioCyciMSP754476:GLGH-2888-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequences of Methylophaga sp. strain JAM1 and Methylophaga sp. strain JAM7."
    Villeneuve C., Martineau C., Mauffrey F., Villemur R.
    J. Bacteriol. 194:4126-4127(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JAM1Imported.

Entry informationi

Entry nameiI1XMR6_METNJ
AccessioniPrimary (citable) accession number: I1XMR6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: July 22, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.