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I1WP44

- I1WP44_BURP2

UniProt

I1WP44 - I1WP44_BURP2

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Protein
Elongation factor Tu
Gene
tuf, BP1026B_I3445, BP1026B_I3460
Organism
Burkholderia pseudomallei (strain 1026b)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBPSE884204:GLA4-3445-MONOMER.
    BPSE884204:GLA4-3460-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:BP1026B_I3445Imported, BP1026B_I3460Imported
    OrganismiBurkholderia pseudomallei (strain 1026b)Imported
    Taxonomic identifieri884204 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
    ProteomesiUP000010087: Chromosome 1

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I1WP44-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKFERTK PHVNVGTIGH VDHGKTTLTA AIATVLSAKF GGEAKKYDEI    50
    DAAPEEKARG ITINTAHIEY ETANRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFLNKCDM VDDAELLELV 150
    EMEVRELLSK YDFPGDDTPI IKGSAKLALE GDKGELGEVA IMNLADALDT 200
    YIPTPERAVD GAFLMPVEDV FSISGRGTVV TGRVERGVIK VGEEIEIVGI 250
    KATAKTTCTG VEMFRKLLDQ GQAGDNVGIL LRGTKREDVE RGQVLAKPGS 300
    ITPHTHFTAE VYVLSKDEGG RHTPFFNNYR PQFYFRTTDV TGSIELPKDK 350
    EMVMPGDNVS ITVKLIAPIA MEEGLRFAIR EGGRTVGAGV VAKIIE 396
    Length:396
    Mass (Da):42,991
    Last modified:July 11, 2012 - v1
    Checksum:i4A60D806CDFF494C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002833 Genomic DNA. Translation: AFI68024.1.
    CP002833 Genomic DNA. Translation: AFI68038.1.
    RefSeqiYP_006276422.1. NC_017831.1.
    YP_006276436.1. NC_017831.1.

    Genome annotation databases

    EnsemblBacteriaiAFI68024; AFI68024; BP1026B_I3445.
    AFI68038; AFI68038; BP1026B_I3460.
    GeneIDi12831638.
    12831653.
    KEGGibpz:BP1026B_I3445.
    bpz:BP1026B_I3460.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002833 Genomic DNA. Translation: AFI68024.1 .
    CP002833 Genomic DNA. Translation: AFI68038.1 .
    RefSeqi YP_006276422.1. NC_017831.1.
    YP_006276436.1. NC_017831.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFI68024 ; AFI68024 ; BP1026B_I3445 .
    AFI68038 ; AFI68038 ; BP1026B_I3460 .
    GeneIDi 12831638.
    12831653.
    KEGGi bpz:BP1026B_I3445.
    bpz:BP1026B_I3460.

    Phylogenomic databases

    KOi K02358.

    Enzyme and pathway databases

    BioCyci BPSE884204:GLA4-3445-MONOMER.
    BPSE884204:GLA4-3460-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 1026bImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1026bImported.

    Entry informationi

    Entry nameiI1WP44_BURP2
    AccessioniPrimary (citable) accession number: I1WP44
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 11, 2012
    Last sequence update: July 11, 2012
    Last modified: July 9, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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