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I1WLH7 (I1WLH7_BURP2) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:BP1026B_I2525 EMBL AFI67121.1
OrganismBurkholderia pseudomallei (strain 1026b) [Complete proteome] [HAMAP] EMBL AFI67121.1
Taxonomic identifier884204 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length994 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2041 By similarity HAMAP-Rule MF_00595
Active site6461 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
I1WLH7 [UniParc].

Last modified July 11, 2012. Version 1.
Checksum: 55D70FE099C4A788

FASTA994108,735
        10         20         30         40         50         60 
MKSSGSARAT RRNAVSSSSA PAHAEPPARR AAKPARKLDG AAARPLAPTN AASAKPQGRT 

        70         80         90        100        110        120 
REDKDRPLFE DIRYLGRLLG DVVREQEGDA VFDVVETIRQ TAVKFRREDD KAAAQTLEKM 

       130        140        150        160        170        180 
LRKLTPEQTV SVVRAFSYFS HLANIAEDRH HNRRRRIHAL AGSAAQAGTV AYALDKLKQA 

       190        200        210        220        230        240 
GDASSKTIKQ FFEGALIVPV LTAHPTEVQR KSILDAQHDI ARLLAERDQP LTARELAHNE 

       250        260        270        280        290        300 
ALLRARVTTL WQTRMLRDAR LTVADEIENA LSYYRATFLD ELPALYADIE EALAEHGLRA 

       310        320        330        340        350        360 
RVPAFFQMGS WIGGDRDGNP NVTAATLDEA ISRQAAVIFE HYLEQVHKLG AELSVSNLLV 

       370        380        390        400        410        420 
GASDALKALA AASPDQSPHR VDEPYRRALI GVYTRLAASA RVRLGEGTVP VRSAGRGAAP 

       430        440        450        460        470        480 
VRATPYADAE EFAADLRVLT DSLALHHGES LATPRLAPLM RAAEVFGFHL ASIDLRQSSD 

       490        500        510        520        530        540 
IHEAVVAELL ARGGVEADYA ALPEADKLRV LLAALADPRP LRSPYLDYSD LAKSELGVLE 

       550        560        570        580        590        600 
RAHAIRAQFG ARAVRNYIIS HTETVSDLVE VLLLQKETGL FEGTLGTPHA NARNGLMVIP 

       610        620        630        640        650        660 
LFETIADLRN ASDIMRAFFA LPGVGELLAH QGHEQEVMLG YSDSNKDGGF LTSNWELYRA 

       670        680        690        700        710        720 
ELALVDLFDE RGIKLRLFHG RGGTVGRGGG PTYQAILSQP PGTVNGQIRL TEQGEVIASK 

       730        740        750        760        770        780 
FANPEIGRRN LETVVAATLE ATLAPHSNAP KQLPAFEAAM QTLSDAAMAS YRALVYETPG 

       790        800        810        820        830        840 
FTDYFFSSTP ITEIAELNIG SRPASRKLQD PKNRKIEDLR AIPWGFSWGQ CRLLLTGWYG 

       850        860        870        880        890        900 
FGSAVAAYLD GAPDAAERGK RVALLKKMNK TWPFFANLLS NMDMVLAKTD LAVASRYAQL 

       910        920        930        940        950        960 
VADKKLRKHV FERIVAEWHR TADALAEITG AHARLAANPL LARSIKNRFP YLDPLNHLQV 

       970        980        990 
ELIKRHRAGD TNARLRRGIH LTINGIAAGL RNTG 

« Hide

References

[1]"Evolution of Burkholderia pseudomallei in recurrent melioidosis."
Hayden H.S., Lim R., Brittnacher M.J., Sims E.H., Ramage E.R., Fong C., Wu Z., Crist E., Chang J., Zhou Y., Radey M., Rohmer L., Haugen E., Gillett W., Wuthiekanun V., Peacock S.J., Kaul R., Miller S.I., Manoil C., Jacobs M.A.
PLoS ONE 7:E36507-E36507(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1026b EMBL AFI67121.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002833 Genomic DNA. Translation: AFI67121.1.
RefSeqYP_006275519.1. NC_017831.1.

3D structure databases

ProteinModelPortalI1WLH7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFI67121; AFI67121; BP1026B_I2525.
GeneID12831342.
KEGGbpz:BP1026B_I2525.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Enzyme and pathway databases

BioCycBPSE884204:GLA4-2525-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameI1WLH7_BURP2
AccessionPrimary (citable) accession number: I1WLH7
Entry history
Integrated into UniProtKB/TrEMBL: July 11, 2012
Last sequence update: July 11, 2012
Last modified: July 9, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)