ID   I1I3L2_BRADI            Unreviewed;       481 AA.
AC   I1I3L2;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE            EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN   Name=100825019 {ECO:0000313|EnsemblPlants:KQJ96451};
GN   ORFNames=BRADI_3g23160v3 {ECO:0000313|EMBL:KQJ96451.1};
OS   Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX   NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQJ96451};
RN   [1] {ECO:0000313|EMBL:KQJ96451.1, ECO:0000313|EnsemblPlants:KQJ96451}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQJ96451.1,
RC   ECO:0000313|EnsemblPlants:KQJ96451};
RX   PubMed=20148030; DOI=10.1038/nature08747;
RG   International Brachypodium Initiative;
RT   "Genome sequencing and analysis of the model grass Brachypodium
RT   distachyon.";
RL   Nature 463:763-768(2010).
RN   [2] {ECO:0000313|EMBL:KQJ96451.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQJ96451.1};
RG   The International Brachypodium Initiative;
RA   Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA   Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA   Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT   "WGS assembly of Brachypodium distachyon.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblPlants:KQJ96451}
RP   IDENTIFICATION.
RC   STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ96451};
RG   EnsemblPlants;
RL   Submitted (AUG-2018) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- PATHWAY: Amino-acid degradation; L-alanine degradation via transaminase
CC       pathway; pyruvate from L-alanine: step 1/1.
CC       {ECO:0000256|ARBA:ARBA00025708}.
CC   -!- PATHWAY: Photosynthesis; C4 acid pathway.
CC       {ECO:0000256|ARBA:ARBA00025709}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. Alanine aminotransferase subfamily.
CC       {ECO:0000256|ARBA:ARBA00025785}.
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DR   EMBL; CM000882; KQJ96451.1; -; Genomic_DNA.
DR   RefSeq; XP_003573850.1; XM_003573802.3.
DR   AlphaFoldDB; I1I3L2; -.
DR   STRING; 15368.I1I3L2; -.
DR   EnsemblPlants; KQJ96451; KQJ96451; BRADI_3g23160v3.
DR   GeneID; 100825019; -.
DR   Gramene; KQJ96451; KQJ96451; BRADI_3g23160v3.
DR   KEGG; bdi:100825019; -.
DR   eggNOG; KOG0258; Eukaryota.
DR   InParanoid; I1I3L2; -.
DR   OMA; YMEFTGF; -.
DR   OrthoDB; 5472891at2759; -.
DR   UniPathway; UPA00322; -.
DR   UniPathway; UPA00528; UER00586.
DR   Proteomes; UP000008810; Chromosome 3.
DR   ExpressionAtlas; I1I3L2; baseline and differential.
DR   GO; GO:0004021; F:L-alanine:2-oxoglutarate aminotransferase activity; IBA:GO_Central.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 1.10.287.1970; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR045088; ALAT1/2-like.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11751; ALANINE AMINOTRANSFERASE; 1.
DR   PANTHER; PTHR11751:SF479; ALANINE TRANSAMINASE; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          106..462
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
SQ   SEQUENCE   481 AA;  52927 MW;  E8E4C87D96ED1238 CRC64;
     MASSVAVENL NPKVLKCEYA VRGEIVIHAQ RLQQQLQNQP GSLPFHEILY CNIGNPQSLG
     QQPVTFFREV LALCDHPYLL QREEIKSLFS ADSISRAKQI LALIPGRATG AYSHSQGIKG
     LRDAIAAGIT ARDGFPANAD DIFLTDGASP GVHLMMQLLI RNEKDGILVP IPQYPLYSAS
     IALHGGALVP YYLNESTGWG LEISDVKKQL EDARSRGIDV RALVVINPGN PTGQVLAEEN
     QYDIVKFCKN EGLVLLADEV YQENIYVDDK KFHSFKKIVR SLGYGEDLPL VSYQSVSKGY
     YGECGKRGGY MEITGFSAPV REQIYKISSV NLCSNITGQI LASLVMNPPK AGDESYASYQ
     AEKDRILTSL ARRAKALEDA FNNLEGITCN KAEGAMYLFP RINLPQKAID AANAANKAPD
     AFYALRLLES TGIVVVPGSG FGQVPGTWHF RCTILPQEEK IPAIISRFKV FHEAFMAEHR
     D
//