Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

I1HW51

- I1HW51_BRADI

UniProt

I1HW51 - I1HW51_BRADI

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

BRADI3G00857

Organism
Brachypodium distachyon (Purple false brome) (Trachynia distachya)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 10 (01 Oct 2014)
      Sequence version 1 (13 Jun 2012)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotation, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    Name:BRADI3G00857Imported
    OrganismiBrachypodium distachyon (Purple false brome) (Trachynia distachya)Imported
    Taxonomic identifieri15368 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeBrachypodieaeBrachypodium
    ProteomesiUP000008810: Chromosome 3

    Subcellular locationi

    Mitochondrion matrix UniRule annotation

    GO - Cellular componenti

    1. mitochondrial matrix Source: UniProtKB-SubCell
    2. pyruvate dehydrogenase complex Source: InterPro

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 lipoyl-binding domain.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotation

    Phylogenomic databases

    KOiK00627.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    I1HW51-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAAHLLRHS RKLRSLRNVV DCERAGLARF FSTGSCSFAV KENGVEKRIG    50
    GSTFSQCDQP GKDLQTFKVS LGGVIRSSTC RRTPSSRISS AVTGINGSLS 100
    RVQVLSSRSF SSSADLPPHQ EIGMPSLSPT MTEGNIAKWV KKEGDKVSPG 150
    EVLCEVETDK ATVEMECMEE GYLAKIVQGD GAKEIKVGEI ICVTVEEEGD 200
    IEKFKDYKPS TSSDAPVAPA ESKPKSEPAE PKVEEKEPAK APEPKALKTA 250
    EPQRSGDRIF SSPLARKLAE DTNVPLSSVK GTGPDGRILK ADIEDYLASV 300
    AKGGKSESFA ASGLDYTDIP NAQIRKVTAN RLLTSKQTIP HYYLTVDTCV 350
    DKLIKLRGEL NPLQDASGGK KISINDLVIK AAALALRKVP QCNSSWMNDF 400
    IRQYNNVNIN VAVQTEHGLF VPVIKDADKK GLGTIAEEVK QLAQRARDNS 450
    LKPADYEGGT FTVSNLGGPF GIKQFCAIIN PPQSAILAIG SAEKRVIPGG 500
    ADGQYEFGSF MSVTMSCDHR VIDGAIGAEF LKAFKGYVEN PTTMLL 546
    Length:546
    Mass (Da):58,777
    Last modified:June 13, 2012 - v1
    Checksum:iEC5FD7735FCCC5F4
    GO

    Sequence databases

    RefSeqiXP_003570870.1. XM_003570822.1.

    Genome annotation databases

    EnsemblPlantsiBRADI3G00857.2; BRADI3G00857.2; BRADI3G00857.
    GeneIDi100830020.
    KEGGibdi:100830020.

    Cross-referencesi

    Sequence databases

    RefSeqi XP_003570870.1. XM_003570822.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi BRADI3G00857.2 ; BRADI3G00857.2 ; BRADI3G00857 .
    GeneIDi 100830020.
    KEGGi bdi:100830020.

    Phylogenomic databases

    KOi K00627.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of the model grass Brachypodium distachyon."
      International Brachypodium Initiative
      Nature 463:763-768(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Bd21Imported.
    2. EnsemblPlants
      Submitted (NOV-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: cv. Bd21Imported.

    Entry informationi

    Entry nameiI1HW51_BRADI
    AccessioniPrimary (citable) accession number: I1HW51
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 13, 2012
    Last sequence update: June 13, 2012
    Last modified: October 1, 2014
    This is version 10 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3