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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene
N/A
Organism
Brachypodium distachyon (Purple false brome) (Trachynia distachya)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei127SubstrateUniRule annotation1
Active sitei212Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
OrganismiBrachypodium distachyon (Purple false brome) (Trachynia distachya)Imported
Taxonomic identifieri15368 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeBrachypodieaeBrachypodium
Proteomesi
  • UP000008810 Componenti: Chromosome 2

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiI1HVM0. differential.

Interactioni

Protein-protein interaction databases

STRINGi15368.BRADI2G62020.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 180NAD_Gly3P_dh_NInterPro annotationAdd BLAST169
Domaini201 – 348NAD_Gly3P_dh_CInterPro annotationAdd BLAST148

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni276 – 277Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I1HVM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENGHGGSKH RVAVIGSGNW GSVASRLLAS NTAKLPSFYD EVRMWVFEET
60 70 80 90 100
LPTGEKLSEC INRANENCKY LPGIKLGTNV IADPDLESAV KDADMLVFVT
110 120 130 140 150
PHQFVEGICK KLVGKLRPGV QAISLIKGME VKMEGPCMIS KLISDTLGIN
160 170 180 190 200
CCVLMGANIA NEIAVEKFSE ATIGYREDKE AASRWAKLFT TPYFLVSVVE
210 220 230 240 250
DIEGVELCGT LKNIVAIAAG LVDGLDMGNN TKAAIMRIGL REMRAFSKLL
260 270 280 290 300
FPSVRDNTFF ESCGVADLIT TCLGGRNRRV AEAFARNGGK RSFDELEAEM
310 320 330 340 350
LHGQKLQGVS TAREVYEVLT YRGWQELFPL LSTVHEICIG QLPPTSIVEY

SSTEG
Length:355
Mass (Da):38,768
Last modified:June 13, 2012 - v1
Checksum:i864C538EAA8F35AC
GO

Genome annotation databases

EnsemblPlantsiBRADI2G62020.2; BRADI2G62020.2; BRADI2G62020.
GrameneiBRADI2G62020.2; BRADI2G62020.2; BRADI2G62020.

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi15368.BRADI2G62020.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiBRADI2G62020.2; BRADI2G62020.2; BRADI2G62020.
GrameneiBRADI2G62020.2; BRADI2G62020.2; BRADI2G62020.

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.

Gene expression databases

ExpressionAtlasiI1HVM0. differential.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiI1HVM0_BRADI
AccessioniPrimary (citable) accession number: I1HVM0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: November 30, 2016
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.