ID   I1GUX1_BRADI            Unreviewed;       678 AA.
AC   I1GUX1;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   24-JAN-2024, entry version 66.
DE   RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   Name=100824574 {ECO:0000313|EnsemblPlants:KQK16493};
GN   ORFNames=BRADI_1g29010v3 {ECO:0000313|EMBL:KQK16493.1};
OS   Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX   NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQK16493};
RN   [1] {ECO:0000313|EMBL:KQK16493.1, ECO:0000313|EnsemblPlants:KQK16493}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQK16493.1,
RC   ECO:0000313|EnsemblPlants:KQK16493};
RX   PubMed=20148030; DOI=10.1038/nature08747;
RG   International Brachypodium Initiative;
RT   "Genome sequencing and analysis of the model grass Brachypodium
RT   distachyon.";
RL   Nature 463:763-768(2010).
RN   [2] {ECO:0000313|EMBL:KQK16493.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQK16493.1};
RG   The International Brachypodium Initiative;
RA   Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA   Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA   Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT   "WGS assembly of Brachypodium distachyon.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblPlants:KQK16493}
RP   IDENTIFICATION.
RC   STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK16493};
RG   EnsemblPlants;
RL   Submitted (AUG-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00358}.
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DR   EMBL; CM000880; KQK16493.1; -; Genomic_DNA.
DR   EMBL; CM000880; PNT75240.1; -; Genomic_DNA.
DR   RefSeq; XP_003563196.1; XM_003563148.3.
DR   AlphaFoldDB; I1GUX1; -.
DR   STRING; 15368.I1GUX1; -.
DR   EnsemblPlants; KQK16493; KQK16493; BRADI_1g29010v3.
DR   EnsemblPlants; PNT75240; PNT75240; BRADI_1g29010v3.
DR   GeneID; 100824574; -.
DR   Gramene; KQK16493; KQK16493; BRADI_1g29010v3.
DR   Gramene; PNT75240; PNT75240; BRADI_1g29010v3.
DR   KEGG; bdi:100824574; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   HOGENOM; CLU_004556_4_1_1; -.
DR   InParanoid; I1GUX1; -.
DR   OMA; IGCYCAQ; -.
DR   OrthoDB; 5481936at2759; -.
DR   Proteomes; UP000008810; Chromosome 1.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0042054; F:histone methyltransferase activity; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   Gene3D; 2.30.280.10; SRA-YDG; 1.
DR   InterPro; IPR025794; H3-K9-MeTrfase_plant.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR036987; SRA-YDG_sf.
DR   InterPro; IPR003105; SRA_YDG.
DR   PANTHER; PTHR45660:SF3; HISTONE-LYSINE N-METHYLTRANSFERASE FAMILY MEMBER SUVH9; 1.
DR   PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF02182; SAD_SRA; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SMART; SM00466; SRA; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS51575; SAM_MT43_SUVAR39_2; 1.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS51015; YDG; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00358}; Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT   DOMAIN          234..382
FT                   /note="YDG"
FT                   /evidence="ECO:0000259|PROSITE:PS51015"
FT   DOMAIN          463..521
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          524..667
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..61
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   678 AA;  74304 MW;  0274ABF453A48ABB CRC64;
     MEVEESSPSS PLSSPSSSPS SDSIDLNFLP FLKREPKSEP ASPEHDPLPP PPPPPPPPQA
     AAAVAVAYVD PTPATPDLSS PAVMTPLQSL PPNPDEDALF AEYCRLASLY LLSAGAGAIV
     QAPTPEAAAP AVVQPGSGSA VKKRRPRSSE LVRVSSLGMR DQIYFRDVVR RARITFESLR
     GLLLKDDERA EALGLPGVVG LGSTDRRRVR ADLRAAALMA DRDLWLNRDR RIVGPIPGIS
     VGDAFFFRME LCVLGIHGQV QAGIDYLTAG RSASGEPIAT SIIVSGGYED DDDRGDILVY
     TGHGGRDPNL HKHCVDQKLE GGNLALERSM AYGIEIRVIR AVKSKRSPVG KVYFYDGLYK
     VVDFWLDRGK AGFGVYKYKM IRIDGQDAMG SVNYRVAERL KVDALSMRPT GYLSFDISMG
     RESMPVALYN DVDDDKDPLL YEYLARPIFP SSAVQGKFAE GGGGCECIEN CSIGCYCAQR
     NGGEFAYDKA GVLLRGKPLV YECGPYCRCP PSCPNRVSQK GLKNRLEVFR SRETGWGVRS
     LDLIKAGAFI CEFSGIVLTH QQSEIVAVNG DCLVHPNRFP PRWLDWGDIS DVYPGYVPPN
     HPAIADLNFS IDVSRARNVA CYFSHSCSPN VFIQFVLFDH YNMSYPHLMI FALENIPPLR
     ELSIDYGMID EWVGKLTM
//