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Protein

Hexokinase

Gene

LOC100639704

Organism
Amphimedon queenslandica (Sponge)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:LOC100639704Imported
OrganismiAmphimedon queenslandica (Sponge)Imported
Taxonomic identifieri400682 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPoriferaDemospongiaeHaploscleridaNiphatidaeAmphimedon
ProteomesiUP000007879 Componenti: Unplaced

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

InParanoidiI1F4T5.
KOiK00844.
OMAiANCEGND.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

I1F4T5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSVGDIVD AFLKPVTKEG LEAISSRLLA QFETGLAKEK HDGEVKMLIT
60 70 80 90 100
YVHNLPSGEE NGDFLALDLG GSNFRVLKIT LDSENRDISQ VDSKFSISEE
110 120 130 140 150
LKKSDQDRLF GFIAESLNNF KKENGITSKL PLGFTFSFPV NQTSLTAGTL
160 170 180 190 200
IHWTKDFKAA NCEGNDVVKM LRDASDARKF PDTDIVALVN DTTGTQMAVG
210 220 230 240 250
YSDQDCHVGV ILGTGTNACY TERLDAVTKF NGDRSQHDKV IINTEWGAFG
260 270 280 290 300
DKGSLKDVIT EFDKAFDSQP EVENGGSQIY EKMISGKYLG EIVRHAMLKL
310 320 330 340 350
INGGVLFGGK SSDVLKKFEG FKSSYLSDIE KGECMDVLKN KCGLDPVTEQ
360 370 380 390 400
DCEYVTQICR AVSTRAARLA AAGIVTIVRK MGREKKCTVA VDGSLYKLHP
410 420 430 440
EFRFRMRAAI NEMLPCNGVI IKESRDGSGR GAALVAAVAK Q
Length:441
Mass (Da):48,195
Last modified:June 13, 2012 - v1
Checksum:i4DAFF33490E90AF4
GO

Sequence databases

RefSeqiXP_003389713.1. XM_003389665.1.

Genome annotation databases

EnsemblMetazoaiPAC:15711074; PAC:15711074; Aqu1.212546.
GeneIDi100639704.
KEGGiaqu:100639704.

Cross-referencesi

Sequence databases

RefSeqiXP_003389713.1. XM_003389665.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiPAC:15711074; PAC:15711074; Aqu1.212546.
GeneIDi100639704.
KEGGiaqu:100639704.

Phylogenomic databases

InParanoidiI1F4T5.
KOiK00844.
OMAiANCEGND.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. EnsemblMetazoa
    Submitted (MAR-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiI1F4T5_AMPQE
AccessioniPrimary (citable) accession number: I1F4T5
Entry historyi
Integrated into UniProtKB/TrEMBL: June 13, 2012
Last sequence update: June 13, 2012
Last modified: April 1, 2015
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.